Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay

A viral model of HIV infection of CD4+ T-cells with virus released period is formulated, and the effect of this released period on the stability of the equilibria is investigated. It is shown that the introduction of the viral released period can destabilize the system, and the period solution may...

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Main Authors: Jun-Yuan Yang, Xiao-Yan Wang, Xue-Zhi Li
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2011/649650
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author Jun-Yuan Yang
Xiao-Yan Wang
Xue-Zhi Li
author_facet Jun-Yuan Yang
Xiao-Yan Wang
Xue-Zhi Li
author_sort Jun-Yuan Yang
collection DOAJ
description A viral model of HIV infection of CD4+ T-cells with virus released period is formulated, and the effect of this released period on the stability of the equilibria is investigated. It is shown that the introduction of the viral released period can destabilize the system, and the period solution may arise. The direction and stability of the Hopf bifurcation are also discussed. Numerical simulations are presented to illustrate the results.
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series Discrete Dynamics in Nature and Society
spelling doaj-art-2649f469717c4d9589140d89fa2eed9c2025-02-03T05:54:06ZengWileyDiscrete Dynamics in Nature and Society1026-02261607-887X2011-01-01201110.1155/2011/649650649650Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released DelayJun-Yuan Yang0Xiao-Yan Wang1Xue-Zhi Li2Department of Applied Mathematics, Yuncheng University, Yuncheng 044000, Shanxi, ChinaDepartment of Applied Mathematics, Yuncheng University, Yuncheng 044000, Shanxi, ChinaDepartment of Mathematics, Xinyang Normal University, Xinyang 464000, Henan, ChinaA viral model of HIV infection of CD4+ T-cells with virus released period is formulated, and the effect of this released period on the stability of the equilibria is investigated. It is shown that the introduction of the viral released period can destabilize the system, and the period solution may arise. The direction and stability of the Hopf bifurcation are also discussed. Numerical simulations are presented to illustrate the results.http://dx.doi.org/10.1155/2011/649650
spellingShingle Jun-Yuan Yang
Xiao-Yan Wang
Xue-Zhi Li
Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay
Discrete Dynamics in Nature and Society
title Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay
title_full Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay
title_fullStr Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay
title_full_unstemmed Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay
title_short Hopf Bifurcation for a Model of HIV Infection of CD4+ T Cells with Virus Released Delay
title_sort hopf bifurcation for a model of hiv infection of cd4 t cells with virus released delay
url http://dx.doi.org/10.1155/2011/649650
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