Time-variant left ventricle models for intracardiac impedance analysis
Cardiovascular diseases are a leading cause of mortality worldwide. Thus, critically ill patients require continuous monitoring of cardiovascular indicators, such as the left ventricular volume (LVV). Although continuous hemodynamic monitoring of patients is desirable, due to technical limitations,...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2024-10-01
|
| Series: | Journal of Electrical Bioimpedance |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/joeb-2024-0015 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832593600084443136 |
|---|---|
| author | Voss Daniel Wemmer Clara Leonhardt Steffen Walter Marian |
| author_facet | Voss Daniel Wemmer Clara Leonhardt Steffen Walter Marian |
| author_sort | Voss Daniel |
| collection | DOAJ |
| description | Cardiovascular diseases are a leading cause of mortality worldwide. Thus, critically ill patients require continuous monitoring of cardiovascular indicators, such as the left ventricular volume (LVV). Although continuous hemodynamic monitoring of patients is desirable, due to technical limitations, current measurement technologies either require manual intervention of the physician or only provide inaccurate results. Intracardiac impedance measurements are a promising approach for continuous assessment of cardiac function. However, developing and evaluating these methods requires a simulation model of the left ventricle with cardiac motion during an entire cardiac cycle. While many models exist for a fixed ventricle size, to date, no freely available models incorporate time and represent the cardiac motion during a complete cardiac cycle. Therefore, we developed four cardiacmechanical left ventricular models with varying ventricle sizes and complexities. Each model focuses on a different aspect of the geometric shape, thus allowing an isolated analysis of the different influences. This paper presents the development of the models and initial results of the impedance analysis. All measured admittances exhibit a high resemblance for all models and a strong, non-linear correlation with the LVV. A comparison between the models shows how the different geometries affect the impedance. The models, thus, provide a useful basis for the development of LVV estimation algorithms. |
| format | Article |
| id | doaj-art-263e56c92a6e4be495fcf9ad65388e84 |
| institution | Kabale University |
| issn | 1891-5469 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Electrical Bioimpedance |
| spelling | doaj-art-263e56c92a6e4be495fcf9ad65388e842025-01-20T11:09:56ZengSciendoJournal of Electrical Bioimpedance1891-54692024-10-0115113013610.2478/joeb-2024-0015Time-variant left ventricle models for intracardiac impedance analysisVoss Daniel0Wemmer Clara1Leonhardt Steffen2Walter Marian31Chair for Medical Information Technology, RWTH Aachen University, Aachen, Germany1Chair for Medical Information Technology, RWTH Aachen University, Aachen, Germany1Chair for Medical Information Technology, RWTH Aachen University, Aachen, Germany1Chair for Medical Information Technology, RWTH Aachen University, Aachen, GermanyCardiovascular diseases are a leading cause of mortality worldwide. Thus, critically ill patients require continuous monitoring of cardiovascular indicators, such as the left ventricular volume (LVV). Although continuous hemodynamic monitoring of patients is desirable, due to technical limitations, current measurement technologies either require manual intervention of the physician or only provide inaccurate results. Intracardiac impedance measurements are a promising approach for continuous assessment of cardiac function. However, developing and evaluating these methods requires a simulation model of the left ventricle with cardiac motion during an entire cardiac cycle. While many models exist for a fixed ventricle size, to date, no freely available models incorporate time and represent the cardiac motion during a complete cardiac cycle. Therefore, we developed four cardiacmechanical left ventricular models with varying ventricle sizes and complexities. Each model focuses on a different aspect of the geometric shape, thus allowing an isolated analysis of the different influences. This paper presents the development of the models and initial results of the impedance analysis. All measured admittances exhibit a high resemblance for all models and a strong, non-linear correlation with the LVV. A comparison between the models shows how the different geometries affect the impedance. The models, thus, provide a useful basis for the development of LVV estimation algorithms.https://doi.org/10.2478/joeb-2024-0015simulationfemheart geometryleft ventricular volumeintracardiac impedance |
| spellingShingle | Voss Daniel Wemmer Clara Leonhardt Steffen Walter Marian Time-variant left ventricle models for intracardiac impedance analysis Journal of Electrical Bioimpedance simulation fem heart geometry left ventricular volume intracardiac impedance |
| title | Time-variant left ventricle models for intracardiac impedance analysis |
| title_full | Time-variant left ventricle models for intracardiac impedance analysis |
| title_fullStr | Time-variant left ventricle models for intracardiac impedance analysis |
| title_full_unstemmed | Time-variant left ventricle models for intracardiac impedance analysis |
| title_short | Time-variant left ventricle models for intracardiac impedance analysis |
| title_sort | time variant left ventricle models for intracardiac impedance analysis |
| topic | simulation fem heart geometry left ventricular volume intracardiac impedance |
| url | https://doi.org/10.2478/joeb-2024-0015 |
| work_keys_str_mv | AT vossdaniel timevariantleftventriclemodelsforintracardiacimpedanceanalysis AT wemmerclara timevariantleftventriclemodelsforintracardiacimpedanceanalysis AT leonhardtsteffen timevariantleftventriclemodelsforintracardiacimpedanceanalysis AT waltermarian timevariantleftventriclemodelsforintracardiacimpedanceanalysis |