Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome
Abstract Background With the global expansion of aquaculture and the increasing demand for fish meal, identifying appropriate and sustainable alternative protein sources for aquafeeds has become essential. Single-cell protein (SCP), derived from methanotrophic bacteria, presents a promising alternat...
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| Language: | English |
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BMC
2025-02-01
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| Series: | Journal of Animal Science and Biotechnology |
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| Online Access: | https://doi.org/10.1186/s40104-024-01146-w |
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| author | Luke Pilmer Lindsey Woolley Alan Lymbery Chinh Dam Abigail Elizur Md Javed Foysal Gavin Partridge |
| author_facet | Luke Pilmer Lindsey Woolley Alan Lymbery Chinh Dam Abigail Elizur Md Javed Foysal Gavin Partridge |
| author_sort | Luke Pilmer |
| collection | DOAJ |
| description | Abstract Background With the global expansion of aquaculture and the increasing demand for fish meal, identifying appropriate and sustainable alternative protein sources for aquafeeds has become essential. Single-cell protein (SCP), derived from methanotrophic bacteria, presents a promising alternative by converting methane into protein, potentially addressing both the need for alternative protein sources and reducing industrial greenhouse gas emissions. This study aimed to evaluate the effects of different levels of SCP inclusion (0%, 25%, 50%, and 75% fish meal replacement) on the health, gene expression, and gut microbiome of yellowtail kingfish (YTK, Seriola lalandi) following a 35-day growth trial. Results The study found that SCP inclusion at the highest level of fishmeal replacement (75%) induced a mild inflammatory response in the hindgut of the fish. However, micromorphological assessments of the hindgut, serum biochemistry, and gene expression analyses revealed no significant detrimental effects from SCP replacement. Notably, there were indications of improved lipid digestibility with SCP. Furthermore, SCP inclusion significantly enhanced microbial richness and altered the composition of the gut microbiome, introducing beneficial bacterial taxa that may contribute to improved gut health and resilience. Conclusions This study highlights SCP as a viable and sustainable alternative to fish meal in YTK diets. The findings suggest that SCP can be included in YTK diets without adverse health effects at moderate levels and may even offer benefits in terms of lipid digestibility and gut microbiome diversity. These results contribute to the advancement of more sustainable aquaculture practices. |
| format | Article |
| id | doaj-art-2638ea35c64d46a8a82f8923555a866a |
| institution | Kabale University |
| issn | 2049-1891 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Animal Science and Biotechnology |
| spelling | doaj-art-2638ea35c64d46a8a82f8923555a866a2025-02-02T12:35:51ZengBMCJournal of Animal Science and Biotechnology2049-18912025-02-0116111510.1186/s40104-024-01146-wExploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiomeLuke Pilmer0Lindsey Woolley1Alan Lymbery2Chinh Dam3Abigail Elizur4Md Javed Foysal5Gavin Partridge6Centre for Sustainable Aquatic Ecosystems, Harry Butler Institute, Murdoch UniversityCentre for Sustainable Aquatic Ecosystems, Harry Butler Institute, Murdoch UniversityCentre for Sustainable Aquatic Ecosystems, Harry Butler Institute, Murdoch UniversityBioinovation Centre, University of the Sunshine CoastBioinovation Centre, University of the Sunshine CoastSchool of Environmental and Life Sciences, The University of NewcastleCentre for Sustainable Aquatic Ecosystems, Harry Butler Institute, Murdoch UniversityAbstract Background With the global expansion of aquaculture and the increasing demand for fish meal, identifying appropriate and sustainable alternative protein sources for aquafeeds has become essential. Single-cell protein (SCP), derived from methanotrophic bacteria, presents a promising alternative by converting methane into protein, potentially addressing both the need for alternative protein sources and reducing industrial greenhouse gas emissions. This study aimed to evaluate the effects of different levels of SCP inclusion (0%, 25%, 50%, and 75% fish meal replacement) on the health, gene expression, and gut microbiome of yellowtail kingfish (YTK, Seriola lalandi) following a 35-day growth trial. Results The study found that SCP inclusion at the highest level of fishmeal replacement (75%) induced a mild inflammatory response in the hindgut of the fish. However, micromorphological assessments of the hindgut, serum biochemistry, and gene expression analyses revealed no significant detrimental effects from SCP replacement. Notably, there were indications of improved lipid digestibility with SCP. Furthermore, SCP inclusion significantly enhanced microbial richness and altered the composition of the gut microbiome, introducing beneficial bacterial taxa that may contribute to improved gut health and resilience. Conclusions This study highlights SCP as a viable and sustainable alternative to fish meal in YTK diets. The findings suggest that SCP can be included in YTK diets without adverse health effects at moderate levels and may even offer benefits in terms of lipid digestibility and gut microbiome diversity. These results contribute to the advancement of more sustainable aquaculture practices.https://doi.org/10.1186/s40104-024-01146-wAlternative proteinsGene expressionMethanotrophic bacteriaMicrobiomeYellowtail kingfish |
| spellingShingle | Luke Pilmer Lindsey Woolley Alan Lymbery Chinh Dam Abigail Elizur Md Javed Foysal Gavin Partridge Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome Journal of Animal Science and Biotechnology Alternative proteins Gene expression Methanotrophic bacteria Microbiome Yellowtail kingfish |
| title | Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome |
| title_full | Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome |
| title_fullStr | Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome |
| title_full_unstemmed | Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome |
| title_short | Exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish (Seriola lalandi) diets: impacts on health and gut microbiome |
| title_sort | exploring single cell microbial protein as a sustainable fishmeal alternative in yellowtail kingfish seriola lalandi diets impacts on health and gut microbiome |
| topic | Alternative proteins Gene expression Methanotrophic bacteria Microbiome Yellowtail kingfish |
| url | https://doi.org/10.1186/s40104-024-01146-w |
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