Protocol on utilizing murine gastric cancer organoids for modeling subcutaneous, orthotopic primary, and liver metastatic disease in mice

Protocol on utilizing murine gastric cancer organoids for modeling subcutaneous, orthotopic primary, and liver metastatic disease in mice

Summary: Tumor initiation, growth, and spread are influenced by cancer cell intrinsic and tissue microenvironment factors of the organ the tumor resides in. Here, we provide a protocol on utilizing murine gastric cancer (GC) organoids as transplantable mouse models for subcutaneous, orthotopic prima...

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Bibliographic Details
Main Authors: Joshua Konecnik, Ryan N. O’Keefe, Kiruthiga Raghunathan, Saumya P. Jacob, Megan O’Brien, Anne Huber, Purva Trivedi, Christine Dijkstra, Amr H. Allam, Michael Buchert, Matthias Ernst, Moritz F. Eissmann
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:STAR Protocols
Subjects:
Cancer
Model Organisms
Organoids
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672500190X
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