Mast cells-intestinal cancer cells crosstalk is mediated by TNF-alpha and sustained by the IL-33/ST2 axis

Abstract It is common knowledge that mast cells (MCs) exert different roles in the gastrointestinal tract, from the maintenance of homeostasis to the onset and propagation of different gut diseases such as food allergies, infections, inflammation, and cancer. However, the mechanisms through which MC...

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Bibliographic Details
Main Authors: Chiara Dal Secco, Silvia Tonon, Caterina Trevisan, Eleonora Martinis, Viviana Valeri, Marta Codrich, Gianluca Tell, Barbara Frossi, Carlo E. M. Pucillo
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Online Access:https://doi.org/10.1007/s00262-025-04054-8
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