Macrophage Migration Inhibitory Factor in Protozoan Infections
Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of paras...
Saved in:
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
|
Series: | Journal of Parasitology Research |
Online Access: | http://dx.doi.org/10.1155/2012/413052 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832559401192390656 |
---|---|
author | Marcelo T. Bozza Yuri C. Martins Letícia A. M. Carneiro Claudia N. Paiva |
author_facet | Marcelo T. Bozza Yuri C. Martins Letícia A. M. Carneiro Claudia N. Paiva |
author_sort | Marcelo T. Bozza |
collection | DOAJ |
description | Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation. |
format | Article |
id | doaj-art-25eb38d0ee4b4fec977642eec8a6abb5 |
institution | Kabale University |
issn | 2090-0023 2090-0031 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Parasitology Research |
spelling | doaj-art-25eb38d0ee4b4fec977642eec8a6abb52025-02-03T01:30:10ZengWileyJournal of Parasitology Research2090-00232090-00312012-01-01201210.1155/2012/413052413052Macrophage Migration Inhibitory Factor in Protozoan InfectionsMarcelo T. Bozza0Yuri C. Martins1Letícia A. M. Carneiro2Claudia N. Paiva3Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilLaboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilLaboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilLaboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilMacrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation.http://dx.doi.org/10.1155/2012/413052 |
spellingShingle | Marcelo T. Bozza Yuri C. Martins Letícia A. M. Carneiro Claudia N. Paiva Macrophage Migration Inhibitory Factor in Protozoan Infections Journal of Parasitology Research |
title | Macrophage Migration Inhibitory Factor in Protozoan Infections |
title_full | Macrophage Migration Inhibitory Factor in Protozoan Infections |
title_fullStr | Macrophage Migration Inhibitory Factor in Protozoan Infections |
title_full_unstemmed | Macrophage Migration Inhibitory Factor in Protozoan Infections |
title_short | Macrophage Migration Inhibitory Factor in Protozoan Infections |
title_sort | macrophage migration inhibitory factor in protozoan infections |
url | http://dx.doi.org/10.1155/2012/413052 |
work_keys_str_mv | AT marcelotbozza macrophagemigrationinhibitoryfactorinprotozoaninfections AT yuricmartins macrophagemigrationinhibitoryfactorinprotozoaninfections AT leticiaamcarneiro macrophagemigrationinhibitoryfactorinprotozoaninfections AT claudianpaiva macrophagemigrationinhibitoryfactorinprotozoaninfections |