Macrophage Migration Inhibitory Factor in Protozoan Infections

Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of paras...

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Main Authors: Marcelo T. Bozza, Yuri C. Martins, Letícia A. M. Carneiro, Claudia N. Paiva
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Parasitology Research
Online Access:http://dx.doi.org/10.1155/2012/413052
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author Marcelo T. Bozza
Yuri C. Martins
Letícia A. M. Carneiro
Claudia N. Paiva
author_facet Marcelo T. Bozza
Yuri C. Martins
Letícia A. M. Carneiro
Claudia N. Paiva
author_sort Marcelo T. Bozza
collection DOAJ
description Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation.
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institution Kabale University
issn 2090-0023
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language English
publishDate 2012-01-01
publisher Wiley
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series Journal of Parasitology Research
spelling doaj-art-25eb38d0ee4b4fec977642eec8a6abb52025-02-03T01:30:10ZengWileyJournal of Parasitology Research2090-00232090-00312012-01-01201210.1155/2012/413052413052Macrophage Migration Inhibitory Factor in Protozoan InfectionsMarcelo T. Bozza0Yuri C. Martins1Letícia A. M. Carneiro2Claudia N. Paiva3Laboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilLaboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilLaboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilLaboratório de Inflamação e Imunidade, Departamento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, 21941-902, Rio de Janeiro, RJ, BrazilMacrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a general trend, MIF participates in the control of parasite burden at the expense of promoting tissue damage due to increased inflammation.http://dx.doi.org/10.1155/2012/413052
spellingShingle Marcelo T. Bozza
Yuri C. Martins
Letícia A. M. Carneiro
Claudia N. Paiva
Macrophage Migration Inhibitory Factor in Protozoan Infections
Journal of Parasitology Research
title Macrophage Migration Inhibitory Factor in Protozoan Infections
title_full Macrophage Migration Inhibitory Factor in Protozoan Infections
title_fullStr Macrophage Migration Inhibitory Factor in Protozoan Infections
title_full_unstemmed Macrophage Migration Inhibitory Factor in Protozoan Infections
title_short Macrophage Migration Inhibitory Factor in Protozoan Infections
title_sort macrophage migration inhibitory factor in protozoan infections
url http://dx.doi.org/10.1155/2012/413052
work_keys_str_mv AT marcelotbozza macrophagemigrationinhibitoryfactorinprotozoaninfections
AT yuricmartins macrophagemigrationinhibitoryfactorinprotozoaninfections
AT leticiaamcarneiro macrophagemigrationinhibitoryfactorinprotozoaninfections
AT claudianpaiva macrophagemigrationinhibitoryfactorinprotozoaninfections