Optimizing Prognostic Assessment in High‐Risk Head and Neck Squamous Cell Carcinomas: The Impact of Tumor Budding and a Novel Histomorphological Scoring System

Optimizing Prognostic Assessment in High‐Risk Head and Neck Squamous Cell Carcinomas: The Impact of Tumor Budding and a Novel Histomorphological Scoring System

ABSTRACT Background Head and neck squamous cell carcinomas (HNSCC) pose significant clinical challenges, particularly in high‐risk cases with positive lymph node status. Current prognostic biomarkers are often costly and methodologically demanding. In this regard, histomorphological biomarkers such...

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Bibliographic Details
Main Authors: Moritz Knebel, Jan Philipp Kühn, Sandrina Körner, Felix Braun, Lukas Brust, Silke Wemmert, Sigrun Smola, Martin Ertz, Mathias Wagner, Bernhard Schick, Luc G. T. Morris, Maximilian Linxweiler, Gilbert Georg Klamminger
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Cancer Medicine
Subjects:
HNSCC
prognostication
tumor budding
Online Access:https://doi.org/10.1002/cam4.70685
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