A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission

In this study, the co-infection of HIV and cholera model has been developed and analyzed. The new fractional-order derivative is applied and the behavior of the solution is interpreted. The order of new generalized fractional-order derivative implication is presented. A new method is incorporated to...

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Main Authors: Kumama Regassa Cheneke, Koya Purnachandra Rao, Gereme Kenassa Edesssa
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Mathematics and Mathematical Sciences
Online Access:http://dx.doi.org/10.1155/2022/7965145
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author Kumama Regassa Cheneke
Koya Purnachandra Rao
Gereme Kenassa Edesssa
author_facet Kumama Regassa Cheneke
Koya Purnachandra Rao
Gereme Kenassa Edesssa
author_sort Kumama Regassa Cheneke
collection DOAJ
description In this study, the co-infection of HIV and cholera model has been developed and analyzed. The new fractional-order derivative is applied and the behavior of the solution is interpreted. The order of new generalized fractional-order derivative implication is presented. A new method is incorporated to determine the forward bifurcation at a threshold  R0=1. The developed method is used to determine the stability of steady-state points. The full model and the submodels’ disease-free equilibrium are locally asymptotically stable if the corresponding reproduction number is less than one and unstable if the production number is greater than one. The only HIV model exhibits forward bifurcation at the threshold point,  R0=1. The numerical simulations solutions obtained using a new generalized fractional-order derivative shows that the total human population size approaches the disease-free equilibrium if the order of the fractional derivative is higher. Also, the simulated results show that the memory effects toward the invading disease are less whenever the order of the fractional derivative is near 0 but higher whenever the order of the fractional derivative is near 1. Furthermore, V. cholerae concentration in the environment increases whenever the intrinsic growth rate increases. The numerical solutions are carried out using MATLAB software.
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spelling doaj-art-25c3f979f5d84168883be110a70bd4d12025-02-03T01:20:11ZengWileyInternational Journal of Mathematics and Mathematical Sciences1687-04252022-01-01202210.1155/2022/7965145A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic TransmissionKumama Regassa Cheneke0Koya Purnachandra Rao1Gereme Kenassa Edesssa2Department of MathematicsDepartment of MathematicsDepartment of MathematicsIn this study, the co-infection of HIV and cholera model has been developed and analyzed. The new fractional-order derivative is applied and the behavior of the solution is interpreted. The order of new generalized fractional-order derivative implication is presented. A new method is incorporated to determine the forward bifurcation at a threshold  R0=1. The developed method is used to determine the stability of steady-state points. The full model and the submodels’ disease-free equilibrium are locally asymptotically stable if the corresponding reproduction number is less than one and unstable if the production number is greater than one. The only HIV model exhibits forward bifurcation at the threshold point,  R0=1. The numerical simulations solutions obtained using a new generalized fractional-order derivative shows that the total human population size approaches the disease-free equilibrium if the order of the fractional derivative is higher. Also, the simulated results show that the memory effects toward the invading disease are less whenever the order of the fractional derivative is near 0 but higher whenever the order of the fractional derivative is near 1. Furthermore, V. cholerae concentration in the environment increases whenever the intrinsic growth rate increases. The numerical solutions are carried out using MATLAB software.http://dx.doi.org/10.1155/2022/7965145
spellingShingle Kumama Regassa Cheneke
Koya Purnachandra Rao
Gereme Kenassa Edesssa
A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission
International Journal of Mathematics and Mathematical Sciences
title A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission
title_full A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission
title_fullStr A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission
title_full_unstemmed A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission
title_short A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission
title_sort new generalized fractional order derivative and bifurcation analysis of cholera and human immunodeficiency co infection dynamic transmission
url http://dx.doi.org/10.1155/2022/7965145
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