Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental Protocols

Mental health is influenced by the fast-paced nature of life. In this scenario, stressful events play an important role. Extensive research has been carried out to develop non-invasive devices for stress detection, which primarily use physiological data and, more recently, artificial intelligence al...

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Main Authors: Matteo Raggi, Lee J. Moore, Luca Mesin
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10838533/
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author Matteo Raggi
Lee J. Moore
Luca Mesin
author_facet Matteo Raggi
Lee J. Moore
Luca Mesin
author_sort Matteo Raggi
collection DOAJ
description Mental health is influenced by the fast-paced nature of life. In this scenario, stressful events play an important role. Extensive research has been carried out to develop non-invasive devices for stress detection, which primarily use physiological data and, more recently, artificial intelligence algorithms. When developing either a new device or algorithm, tests in controlled environments are preferred, because of the supervision of possible confounding factors while running the experiments. However, because of the extremely subjective perception of stress, the characteristics of the investigated samples, and the conditions under which the experiment is conducted, the data may not be representative of a perceived stressful condition, leading to biases. Given the importance of reliable experimental protocols for stress induction, especially if cortisol level is not monitored, this work aims to present approaches for inducing and assessing acute mental stress in controlled conditions, analyzing the problem from engineering and psychological perspectives. All the phases of the experimental protocol are discussed, examining both the factors that could induce stress and the assessment tools, like questionnaires and physiological signals. The analysis of the latter will be focused on the exogenous factors that may compromise the measures, providing solutions for their mitigation. With this work, researchers with different backgrounds can improve the efficacy of their studies, limiting biases and misleading results.
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spelling doaj-art-25b6b80a1ed94f4cb6c58eb0773259312025-01-21T00:02:00ZengIEEEIEEE Access2169-35362025-01-0113100221004210.1109/ACCESS.2025.352851810838533Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental ProtocolsMatteo Raggi0https://orcid.org/0000-0002-4154-0447Lee J. Moore1https://orcid.org/0000-0001-7394-7762Luca Mesin2https://orcid.org/0000-0002-8239-2348Department of Electronics and Telecommunications, Politecnico di Torino, Turin, ItalyDepartment for Health, University of Bath, Bath, Somerset, U.K.Department of Electronics and Telecommunications, Politecnico di Torino, Turin, ItalyMental health is influenced by the fast-paced nature of life. In this scenario, stressful events play an important role. Extensive research has been carried out to develop non-invasive devices for stress detection, which primarily use physiological data and, more recently, artificial intelligence algorithms. When developing either a new device or algorithm, tests in controlled environments are preferred, because of the supervision of possible confounding factors while running the experiments. However, because of the extremely subjective perception of stress, the characteristics of the investigated samples, and the conditions under which the experiment is conducted, the data may not be representative of a perceived stressful condition, leading to biases. Given the importance of reliable experimental protocols for stress induction, especially if cortisol level is not monitored, this work aims to present approaches for inducing and assessing acute mental stress in controlled conditions, analyzing the problem from engineering and psychological perspectives. All the phases of the experimental protocol are discussed, examining both the factors that could induce stress and the assessment tools, like questionnaires and physiological signals. The analysis of the latter will be focused on the exogenous factors that may compromise the measures, providing solutions for their mitigation. With this work, researchers with different backgrounds can improve the efficacy of their studies, limiting biases and misleading results.https://ieeexplore.ieee.org/document/10838533/Stress monitoringstress assessmentstate anxietyexperimental protocols
spellingShingle Matteo Raggi
Lee J. Moore
Luca Mesin
Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental Protocols
IEEE Access
Stress monitoring
stress assessment
state anxiety
experimental protocols
title Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental Protocols
title_full Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental Protocols
title_fullStr Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental Protocols
title_full_unstemmed Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental Protocols
title_short Inducing and Assessing Acute Mental Stress in Controlled Conditions: Topical Review and Guidelines for Effective Experimental Protocols
title_sort inducing and assessing acute mental stress in controlled conditions topical review and guidelines for effective experimental protocols
topic Stress monitoring
stress assessment
state anxiety
experimental protocols
url https://ieeexplore.ieee.org/document/10838533/
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AT leejmoore inducingandassessingacutementalstressincontrolledconditionstopicalreviewandguidelinesforeffectiveexperimentalprotocols
AT lucamesin inducingandassessingacutementalstressincontrolledconditionstopicalreviewandguidelinesforeffectiveexperimentalprotocols