Mechanistic Investigation into Crystallization of Hydrated Co-Amorphous Systems of Flurbiprofen and Lidocaine

<b>Background:</b> It is generally accepted that water as a plasticizer can decrease the glass transition temperatures (T<sub>g</sub>s) of amorphous drugs and drug delivery systems, resulting in physical instabilities. However, a recent study has reported an anti-plasticizing...

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Bibliographic Details
Main Authors: Xiaoyue Xu, Holger Grohganz, Justyna Knapik-Kowalczuk, Marian Paluch, Thomas Rades
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
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Online Access:https://www.mdpi.com/1999-4923/17/2/175
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