Mechanistic Investigation into Crystallization of Hydrated Co-Amorphous Systems of Flurbiprofen and Lidocaine
<b>Background:</b> It is generally accepted that water as a plasticizer can decrease the glass transition temperatures (T<sub>g</sub>s) of amorphous drugs and drug delivery systems, resulting in physical instabilities. However, a recent study has reported an anti-plasticizing...
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| Main Authors: | Xiaoyue Xu, Holger Grohganz, Justyna Knapik-Kowalczuk, Marian Paluch, Thomas Rades |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/17/2/175 |
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