Oocyte Cryostorage to Preserve Fertility in Oncological Patients
Thanks to the progress in oncostatic treatments, young women affected by cancer have a fairly good chance of surviving the disease and leading a normal post-cancer life. Quite often, however, polychemiotherapy and/or radiotherapy can induce ovarian damage and significantly reduce the content of foll...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2012/525896 |
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| Summary: | Thanks to the progress in oncostatic treatments, young women affected by cancer have a
fairly good chance of surviving the disease and leading a normal post-cancer life. Quite
often, however, polychemiotherapy and/or radiotherapy can induce ovarian damage and
significantly reduce the content of follicles and oocytes inside the ovary, thus predisposing
the patient to menstrual disorders, infertility, and precocious menopause. Several
techniques have been proposed to preserve fertility in these patients; among them oocyte
collection and cryopreservation prior to the oncostatic treatment has been widely applied
in the last decade. The proper indications, the permitting conditions, the available
hormonal stimulation protocols, as well as the effectiveness and limits of this option will be
discussed herein, with a comprehensive and up-to-date review of the two techniques
commonly used to cryostore oocytes, the slow-freezing technique and the vitrification technique. |
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| ISSN: | 1687-9589 1687-9597 |