The Role of the Vagus Nerve in Depressive Disorders: A Literature Review and the Potential of Vagotomy to Create a Depression Phenotype in Rodents

Major depressive disorder (MDD) affects 280 million people worldwide and is a major global health burden due to its link with suicide, physical comorbidities, and inadequate response to pharmacotherapy in many patients. The monoamine theory of depression has provided therapeutic targets, yet explori...

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Bibliographic Details
Main Authors: Ataker F., Pencheva D., Bakalov D.
Format: Article
Language:English
Published: Sciendo 2025-06-01
Series:Acta Medica Bulgarica
Subjects:
Online Access:https://doi.org/10.2478/amb-2025-0051
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