Compensatory increase in oxygen extraction fraction is associated with age-related cerebrovascular disease

Compensatory increase in oxygen extraction fraction is associated with age-related cerebrovascular disease

Cerebrovascular disease is an important contributor to dementia with reductions in cerebral blood flow (CBF) potentially compromising oxygen supply. In early stages, reduced CBF may be associated with a compensatory increase in oxygen extraction fraction (OEF) to maintain the cerebral metabolic rate...

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Bibliographic Details
Main Authors: John McFadden, Julian Matthews, Lauren Scott, Karl Herholz, Ben Dickie, Hamied Haroon, Oliver Sparasci, Saadat Ahmed, Natalia Kyrtata, Geoffrey J.M. Parker, Hedley C.A. Emsley, Joel Handley, Maélène Lohezic, Laura M. Parkes
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:NeuroImage: Clinical
Subjects:
OEF
QSM
CBF
Cerebrovascular disease
Cognitive impairment
Multi-PLD ASL
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158225000166
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