Global stability of the steady states of an epidemic model incorporating intervention strategies

In this paper, we investigate the global stability of the steady states of a general reaction-diffusion epidemiological model with infection force under intervention strategies in a spatially heterogeneous environment. We prove that the reproduction number $\mathcal{R}_0$ can be played an essentia...

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Main Authors: Yongli Cai, Yun Kang, Weiming Wang
Format: Article
Language:English
Published: AIMS Press 2017-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2017056
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author Yongli Cai
Yun Kang
Weiming Wang
author_facet Yongli Cai
Yun Kang
Weiming Wang
author_sort Yongli Cai
collection DOAJ
description In this paper, we investigate the global stability of the steady states of a general reaction-diffusion epidemiological model with infection force under intervention strategies in a spatially heterogeneous environment. We prove that the reproduction number $\mathcal{R}_0$ can be played an essential role in determining whether the disease will extinct or persist: if $\mathcal{R}_0 \lt 1$ , there is a unique disease-free equilibrium which is globally asymptotically stable; and if $\mathcal{R}_0 \gt 1$ , there exists a unique endemic equilibrium which is globally asymptotically stable. Furthermore, we study the relation between $\mathcal{R}_0$ with the diffusion and spatial heterogeneity and find that, it seems very necessary to create a low-risk habitat for the population to effectively control the spread of the epidemic disease. This may provide some potential applications in disease control.
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series Mathematical Biosciences and Engineering
spelling doaj-art-2570606e42bc4a25bd8bde31e8b4540e2025-01-24T02:40:31ZengAIMS PressMathematical Biosciences and Engineering1551-00182017-09-01145&61071108910.3934/mbe.2017056Global stability of the steady states of an epidemic model incorporating intervention strategiesYongli Cai0Yun Kang1Weiming Wang2School of Mathematical Science, Huaiyin Normal University, Huaian 223300, ChinaSciences and Mathematics Faculty, College of Integrative Sciences and Arts, Arizona State University, Mesa, AZ 85212, USASchool of Mathematical Science, Huaiyin Normal University, Huaian 223300, ChinaIn this paper, we investigate the global stability of the steady states of a general reaction-diffusion epidemiological model with infection force under intervention strategies in a spatially heterogeneous environment. We prove that the reproduction number $\mathcal{R}_0$ can be played an essential role in determining whether the disease will extinct or persist: if $\mathcal{R}_0 \lt 1$ , there is a unique disease-free equilibrium which is globally asymptotically stable; and if $\mathcal{R}_0 \gt 1$ , there exists a unique endemic equilibrium which is globally asymptotically stable. Furthermore, we study the relation between $\mathcal{R}_0$ with the diffusion and spatial heterogeneity and find that, it seems very necessary to create a low-risk habitat for the population to effectively control the spread of the epidemic disease. This may provide some potential applications in disease control.https://www.aimspress.com/article/doi/10.3934/mbe.2017056basic reproduction numberdisease-free equilibriumendemicspatial heterogeneity
spellingShingle Yongli Cai
Yun Kang
Weiming Wang
Global stability of the steady states of an epidemic model incorporating intervention strategies
Mathematical Biosciences and Engineering
basic reproduction number
disease-free equilibrium
endemic
spatial heterogeneity
title Global stability of the steady states of an epidemic model incorporating intervention strategies
title_full Global stability of the steady states of an epidemic model incorporating intervention strategies
title_fullStr Global stability of the steady states of an epidemic model incorporating intervention strategies
title_full_unstemmed Global stability of the steady states of an epidemic model incorporating intervention strategies
title_short Global stability of the steady states of an epidemic model incorporating intervention strategies
title_sort global stability of the steady states of an epidemic model incorporating intervention strategies
topic basic reproduction number
disease-free equilibrium
endemic
spatial heterogeneity
url https://www.aimspress.com/article/doi/10.3934/mbe.2017056
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AT yunkang globalstabilityofthesteadystatesofanepidemicmodelincorporatinginterventionstrategies
AT weimingwang globalstabilityofthesteadystatesofanepidemicmodelincorporatinginterventionstrategies