Etiopathogenic Considerations of Alcohol in Pancreatitis

There is a close relation between alcohol intake and pancreas deleterious effects. Between 80 and 100 grams alcohol daily for more than three or 5 years may damage the pancreas and inflame it. This work was aimed at explaining the alcohol action mechanisms in the pancreas, so as describing the physi...

Full description

Saved in:
Bibliographic Details
Main Authors: Leonardo Javier Pérez Ponce, Roberto Carlos Barletta Farías, Gabriela Castro Vega, Jorge Bárbaro Barletta Farías, Milagros Lisset León Regal, Lázaro Array Brito
Format: Article
Language:Spanish
Published: Universidad de las Ciencias Médicas de Cienfuegos 2017-02-01
Series:Revista Finlay
Subjects:
Online Access:https://revfinlay.sld.cu/index.php/finlay/article/view/467
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832577442761408512
author Leonardo Javier Pérez Ponce
Roberto Carlos Barletta Farías
Gabriela Castro Vega
Jorge Bárbaro Barletta Farías
Milagros Lisset León Regal
Lázaro Array Brito
author_facet Leonardo Javier Pérez Ponce
Roberto Carlos Barletta Farías
Gabriela Castro Vega
Jorge Bárbaro Barletta Farías
Milagros Lisset León Regal
Lázaro Array Brito
author_sort Leonardo Javier Pérez Ponce
collection DOAJ
description There is a close relation between alcohol intake and pancreas deleterious effects. Between 80 and 100 grams alcohol daily for more than three or 5 years may damage the pancreas and inflame it. This work was aimed at explaining the alcohol action mechanisms in the pancreas, so as describing the physiopathology of acute and chronic pancreatitis. For that, a total of 24 bibliographic sources were consulted, among them journal articles, books and others, accessed through the main information managers. It was concluded that the pancreas may brake down alcohol either via oxidative or non oxidative way, causing an increase of free radicals, pancreatic edema, intracellular trypsin activation, and the induction of proinflammatory transcription factors, which stimulate the stellate cells leading to a systemic inflammatory response and organic insufficiency.
format Article
id doaj-art-254840ff298a481994d888193640cc09
institution Kabale University
issn 2221-2434
language Spanish
publishDate 2017-02-01
publisher Universidad de las Ciencias Médicas de Cienfuegos
record_format Article
series Revista Finlay
spelling doaj-art-254840ff298a481994d888193640cc092025-01-30T21:21:58ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342017-02-01713346311Etiopathogenic Considerations of Alcohol in PancreatitisLeonardo Javier Pérez Ponce0Roberto Carlos Barletta Farías1Gabriela Castro Vega2Jorge Bárbaro Barletta Farías3Milagros Lisset León Regal4Lázaro Array Brito5Universidad de Ciencias Médicas. Cienfuegos.Universidad de Ciencias Médicas. Cienfuegos.Universidad de Ciencias Médicas. Cienfuegos.Universidad de Ciencias Médicas. Cienfuegos.Universidad de Ciencias Médicas. Cienfuegos.Hospital General Universitario Dr. Gustavo Aldereguía Lima. Cienfuegos.There is a close relation between alcohol intake and pancreas deleterious effects. Between 80 and 100 grams alcohol daily for more than three or 5 years may damage the pancreas and inflame it. This work was aimed at explaining the alcohol action mechanisms in the pancreas, so as describing the physiopathology of acute and chronic pancreatitis. For that, a total of 24 bibliographic sources were consulted, among them journal articles, books and others, accessed through the main information managers. It was concluded that the pancreas may brake down alcohol either via oxidative or non oxidative way, causing an increase of free radicals, pancreatic edema, intracellular trypsin activation, and the induction of proinflammatory transcription factors, which stimulate the stellate cells leading to a systemic inflammatory response and organic insufficiency.https://revfinlay.sld.cu/index.php/finlay/article/view/467pancreatitis alcohólicapancreatitis crónica
spellingShingle Leonardo Javier Pérez Ponce
Roberto Carlos Barletta Farías
Gabriela Castro Vega
Jorge Bárbaro Barletta Farías
Milagros Lisset León Regal
Lázaro Array Brito
Etiopathogenic Considerations of Alcohol in Pancreatitis
Revista Finlay
pancreatitis alcohólica
pancreatitis crónica
title Etiopathogenic Considerations of Alcohol in Pancreatitis
title_full Etiopathogenic Considerations of Alcohol in Pancreatitis
title_fullStr Etiopathogenic Considerations of Alcohol in Pancreatitis
title_full_unstemmed Etiopathogenic Considerations of Alcohol in Pancreatitis
title_short Etiopathogenic Considerations of Alcohol in Pancreatitis
title_sort etiopathogenic considerations of alcohol in pancreatitis
topic pancreatitis alcohólica
pancreatitis crónica
url https://revfinlay.sld.cu/index.php/finlay/article/view/467
work_keys_str_mv AT leonardojavierperezponce etiopathogenicconsiderationsofalcoholinpancreatitis
AT robertocarlosbarlettafarias etiopathogenicconsiderationsofalcoholinpancreatitis
AT gabrielacastrovega etiopathogenicconsiderationsofalcoholinpancreatitis
AT jorgebarbarobarlettafarias etiopathogenicconsiderationsofalcoholinpancreatitis
AT milagroslissetleonregal etiopathogenicconsiderationsofalcoholinpancreatitis
AT lazaroarraybrito etiopathogenicconsiderationsofalcoholinpancreatitis