Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model
Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of loc...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/2604032 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832563547174862848 |
|---|---|
| author | Mu Yang Jian-Xin Dong Lu-Bin Li Hai-Jie Che Jun Yong Fu-Bo Song Tao Wang Jv-Wen Zhang |
| author_facet | Mu Yang Jian-Xin Dong Lu-Bin Li Hai-Jie Che Jun Yong Fu-Bo Song Tao Wang Jv-Wen Zhang |
| author_sort | Mu Yang |
| collection | DOAJ |
| description | Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postconditioning (LIPo) and remote ischemia postconditioning (RIPo) on intestinal I/R injury. We concluded that LIPo affords protection in intestinal I/R injury in a comparable fashion with RIPo by decreasing oxidative stress, neutrophil activation, and apoptosis. |
| format | Article |
| id | doaj-art-2537a3a7484640648963fc81d076adcf |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-2537a3a7484640648963fc81d076adcf2025-02-03T01:13:11ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/26040322604032Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion ModelMu Yang0Jian-Xin Dong1Lu-Bin Li2Hai-Jie Che3Jun Yong4Fu-Bo Song5Tao Wang6Jv-Wen Zhang7Department of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaDepartment of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaDepartment of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaDepartment of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaDepartment of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaDepartment of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaDepartment of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaDepartment of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, ChinaIntestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postconditioning (LIPo) and remote ischemia postconditioning (RIPo) on intestinal I/R injury. We concluded that LIPo affords protection in intestinal I/R injury in a comparable fashion with RIPo by decreasing oxidative stress, neutrophil activation, and apoptosis.http://dx.doi.org/10.1155/2016/2604032 |
| spellingShingle | Mu Yang Jian-Xin Dong Lu-Bin Li Hai-Jie Che Jun Yong Fu-Bo Song Tao Wang Jv-Wen Zhang Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model Gastroenterology Research and Practice |
| title | Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model |
| title_full | Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model |
| title_fullStr | Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model |
| title_full_unstemmed | Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model |
| title_short | Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model |
| title_sort | local and remote postconditioning decrease intestinal injury in a rabbit ischemia reperfusion model |
| url | http://dx.doi.org/10.1155/2016/2604032 |
| work_keys_str_mv | AT muyang localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel AT jianxindong localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel AT lubinli localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel AT haijieche localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel AT junyong localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel AT fubosong localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel AT taowang localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel AT jvwenzhang localandremotepostconditioningdecreaseintestinalinjuryinarabbitischemiareperfusionmodel |