To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City
Insulin resistance is a condition in which persons with type 2 diabetes make insulin but is unable to use it properly to transfer glucose into cells, resulting in high blood glucose levels. Obesity, particularly visceral fat (fat surrounding the organs) is a major cause of insulin resistance. The h...
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middle technical university
2022-09-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/538 |
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| author | Safa Nadhum Mohammed Walaa Esmael Jassim Najah Ali Mohammed |
| author_facet | Safa Nadhum Mohammed Walaa Esmael Jassim Najah Ali Mohammed |
| author_sort | Safa Nadhum Mohammed |
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Insulin resistance is a condition in which persons with type 2 diabetes make insulin but is unable to use it properly to transfer glucose into cells, resulting in high blood glucose levels. Obesity, particularly visceral fat (fat surrounding the organs) is a major cause of insulin resistance. The homeostasis model evaluation is the gold standard method for determining whether or not a person is insulin resistant. This article tries to investigate the development of the values of some parameters among type 2- diabetic patients versus normal levels of healthy control groups these parameters included FBS, HbAIc (%), FIL, HOMAIR age BMI and lipid profile. The results found that the means values of FBS(mg/dl), HbAIc (%), FIL (miu /L), HOMAIR were (175.96± 39.68, 9.74±1.82 , 18.99±5.98 , 8.136±2.53) respectively versus normal levels of control group (85.44±7.58, 4.92±.500 , 5.79 ± 0.5, 1.22±0.17). While means of age and BMI (kg/m²) of cases were (54.27±13.35, 32.20±2.23) versus the mean for the control group (47.12±10.77, 26.04±1.65) respectively. The levels of total cholesterol (mg/dl), triglycerides (mg/dl), LDL (mg/dl) and VLDL (mg/dl) among type-2 diabetic patients were(238.19±8.27, 183.48±7.66, 117.20±8.59, 36.69±4.28) respectively versus normal concentrations among control groups with mean values (146.03±7.48, 137.54±7.43, 87.55±6.92, 23.6±5.58) respectively, While the mean value of HDL-C was (40.34±9.82) in patients and (52.31± 4.94) in control. In all these parameters there were highly significant differences between case and control (with (p-value= >0.001) and the mean values of patients with type 2 DM were more than control except the values of HDL-C were in patients less than in control. This study found that the results of the tests FBS, HbAIc (%), age BMI and lipid profile in patients with diabetes type 2 in comparison to the control group have a significant correlation with FIL, HOMAIR.
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| format | Article |
| id | doaj-art-252ed0ab74e648199bd7686ba0a3fd13 |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | middle technical university |
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| series | Journal of Techniques |
| spelling | doaj-art-252ed0ab74e648199bd7686ba0a3fd132025-01-19T11:07:12Zengmiddle technical universityJournal of Techniques1818-653X2708-83832022-09-014310.51173/jt.v4i3.538To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah CitySafa Nadhum Mohammed0Walaa Esmael Jassim1Najah Ali Mohammed 2Diyala Health Department - Public Health Department - Public Health LaboratoryCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqInstitute of Medical Technology / Baghdad, Middle Technical University, Baghdad, Iraq Insulin resistance is a condition in which persons with type 2 diabetes make insulin but is unable to use it properly to transfer glucose into cells, resulting in high blood glucose levels. Obesity, particularly visceral fat (fat surrounding the organs) is a major cause of insulin resistance. The homeostasis model evaluation is the gold standard method for determining whether or not a person is insulin resistant. This article tries to investigate the development of the values of some parameters among type 2- diabetic patients versus normal levels of healthy control groups these parameters included FBS, HbAIc (%), FIL, HOMAIR age BMI and lipid profile. The results found that the means values of FBS(mg/dl), HbAIc (%), FIL (miu /L), HOMAIR were (175.96± 39.68, 9.74±1.82 , 18.99±5.98 , 8.136±2.53) respectively versus normal levels of control group (85.44±7.58, 4.92±.500 , 5.79 ± 0.5, 1.22±0.17). While means of age and BMI (kg/m²) of cases were (54.27±13.35, 32.20±2.23) versus the mean for the control group (47.12±10.77, 26.04±1.65) respectively. The levels of total cholesterol (mg/dl), triglycerides (mg/dl), LDL (mg/dl) and VLDL (mg/dl) among type-2 diabetic patients were(238.19±8.27, 183.48±7.66, 117.20±8.59, 36.69±4.28) respectively versus normal concentrations among control groups with mean values (146.03±7.48, 137.54±7.43, 87.55±6.92, 23.6±5.58) respectively, While the mean value of HDL-C was (40.34±9.82) in patients and (52.31± 4.94) in control. In all these parameters there were highly significant differences between case and control (with (p-value= >0.001) and the mean values of patients with type 2 DM were more than control except the values of HDL-C were in patients less than in control. This study found that the results of the tests FBS, HbAIc (%), age BMI and lipid profile in patients with diabetes type 2 in comparison to the control group have a significant correlation with FIL, HOMAIR. https://journal.mtu.edu.iq/index.php/MTU/article/view/538Insulin resistanceHOMAIRLipid profileBMIType 2 diabetes |
| spellingShingle | Safa Nadhum Mohammed Walaa Esmael Jassim Najah Ali Mohammed To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City Journal of Techniques Insulin resistance HOMAIR Lipid profile BMI Type 2 diabetes |
| title | To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City |
| title_full | To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City |
| title_fullStr | To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City |
| title_full_unstemmed | To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City |
| title_short | To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City |
| title_sort | to investigate the associations of dyslipidemia and bmi as risk factors leading to insulin resistance and development of type2 diabetes mellitus in baqubah city |
| topic | Insulin resistance HOMAIR Lipid profile BMI Type 2 diabetes |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/538 |
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