Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohort

Objective: Low maternal education is a risk factor for early childhood development (ECD), while exclusive breastfeeding (EBF) is a protective factor. This study examined the association between maternal education and ECD outcomes such as cognitive, language, and motor domains and whether EBF modifie...

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Main Authors: Luiza Alves Ford, Gabriela Buccini, Amanda Castelo Saragosa, Isadora de Araújo Martins, Janaína Matos Moreira, Stela Maris Aguiar Lemos, Claudia Regina Lindgren Alves, Vivian Mara Gonçalves de Oliveira Azevedo
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Jornal de Pediatria
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Online Access:http://www.sciencedirect.com/science/article/pii/S0021755725000543
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author Luiza Alves Ford
Gabriela Buccini
Amanda Castelo Saragosa
Isadora de Araújo Martins
Janaína Matos Moreira
Stela Maris Aguiar Lemos
Claudia Regina Lindgren Alves
Vivian Mara Gonçalves de Oliveira Azevedo
author_facet Luiza Alves Ford
Gabriela Buccini
Amanda Castelo Saragosa
Isadora de Araújo Martins
Janaína Matos Moreira
Stela Maris Aguiar Lemos
Claudia Regina Lindgren Alves
Vivian Mara Gonçalves de Oliveira Azevedo
author_sort Luiza Alves Ford
collection DOAJ
description Objective: Low maternal education is a risk factor for early childhood development (ECD), while exclusive breastfeeding (EBF) is a protective factor. This study examined the association between maternal education and ECD outcomes such as cognitive, language, and motor domains and whether EBF modifies this association in Brazil. Methods: This cross-sectional study analyzed data from a non-probabilistic sample of 12-month-old infants born during the COVID-19. Moderation analyses using the Mann-Whitney test examined the effect of EBF at 6 months (effect modifier) on the relationship between Bayley-III cognitive, language, and motor scores as well as Bayley Global Score (BGS) (outcomes) and maternal education (independent variable). The effect size (r) from the sensitivity analysis of the effect modifier was estimated. Results: A total of 269 full-term infants were evaluated. Higher maternal education was associated with better cognitive, language, and BGS (p < 0.00). EBF was associated with higher cognitive (p < 0.01), language (p < 0.02), and BGS (p < 0.00). EBF modified the effect of low maternal education (<10 years; and 10–12 years) on cognitive score and BGS. Among mothers with >10 years of education, a large effect size of EBF was observed on the BGS (r = 0.51), and a medium effect size was noted in the cognitive domain (r = 0.38). Conclusion: Higher maternal education is associated with better scores on Bayley-III domains, and EBF can modify the effect of lower maternal education on ECD in Brazil. This is the first study to identify EBF as a mechanism to protect ECD in adverse conditions such as low maternal education.
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spelling doaj-art-252d703ac07e42e9a43bd30416e0b9082025-08-20T02:36:30ZengElsevierJornal de Pediatria0021-75572025-07-01101451151910.1016/j.jped.2025.02.004Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohortLuiza Alves Ford0Gabriela Buccini1Amanda Castelo Saragosa2Isadora de Araújo Martins3Janaína Matos Moreira4Stela Maris Aguiar Lemos5Claudia Regina Lindgren Alves6Vivian Mara Gonçalves de Oliveira Azevedo7Universidade Federal de Uberlândia, Uberlandia, MG, BrazilUniversity of Nevada, Las Vegas, United StatesUniversity of Nevada, Las Vegas, United StatesUniversidade Federal de Minas Gerais, Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais, Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais, Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais, Belo Horizonte, MG, BrazilUniversidade Federal de Uberlândia, Uberlandia, MG, Brazil; Corresponding author.Objective: Low maternal education is a risk factor for early childhood development (ECD), while exclusive breastfeeding (EBF) is a protective factor. This study examined the association between maternal education and ECD outcomes such as cognitive, language, and motor domains and whether EBF modifies this association in Brazil. Methods: This cross-sectional study analyzed data from a non-probabilistic sample of 12-month-old infants born during the COVID-19. Moderation analyses using the Mann-Whitney test examined the effect of EBF at 6 months (effect modifier) on the relationship between Bayley-III cognitive, language, and motor scores as well as Bayley Global Score (BGS) (outcomes) and maternal education (independent variable). The effect size (r) from the sensitivity analysis of the effect modifier was estimated. Results: A total of 269 full-term infants were evaluated. Higher maternal education was associated with better cognitive, language, and BGS (p < 0.00). EBF was associated with higher cognitive (p < 0.01), language (p < 0.02), and BGS (p < 0.00). EBF modified the effect of low maternal education (<10 years; and 10–12 years) on cognitive score and BGS. Among mothers with >10 years of education, a large effect size of EBF was observed on the BGS (r = 0.51), and a medium effect size was noted in the cognitive domain (r = 0.38). Conclusion: Higher maternal education is associated with better scores on Bayley-III domains, and EBF can modify the effect of lower maternal education on ECD in Brazil. This is the first study to identify EBF as a mechanism to protect ECD in adverse conditions such as low maternal education.http://www.sciencedirect.com/science/article/pii/S0021755725000543BreastfeedingExclusive breastfeedingChild developmentMaternal educationCOVID-19
spellingShingle Luiza Alves Ford
Gabriela Buccini
Amanda Castelo Saragosa
Isadora de Araújo Martins
Janaína Matos Moreira
Stela Maris Aguiar Lemos
Claudia Regina Lindgren Alves
Vivian Mara Gonçalves de Oliveira Azevedo
Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohort
Jornal de Pediatria
Breastfeeding
Exclusive breastfeeding
Child development
Maternal education
COVID-19
title Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohort
title_full Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohort
title_fullStr Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohort
title_full_unstemmed Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohort
title_short Exclusive breastfeeding modifies the association between maternal education and child development: a cross-sectional study nested in a cohort
title_sort exclusive breastfeeding modifies the association between maternal education and child development a cross sectional study nested in a cohort
topic Breastfeeding
Exclusive breastfeeding
Child development
Maternal education
COVID-19
url http://www.sciencedirect.com/science/article/pii/S0021755725000543
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