Regulation of Immune Function by Polyphenols
Immune dysfunction is caused by various factors, including changes in relevant immune regulators and environmental stress. Immune system imbalance leads to a variety of diseases in humans. Nutrition may play an essential role in immunity by interfering with proinflammatory cytokine synthesis, immune...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2018/1264074 |
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| author | Sujuan Ding Hongmei Jiang Jun Fang |
| author_facet | Sujuan Ding Hongmei Jiang Jun Fang |
| author_sort | Sujuan Ding |
| collection | DOAJ |
| description | Immune dysfunction is caused by various factors, including changes in relevant immune regulators and environmental stress. Immune system imbalance leads to a variety of diseases in humans. Nutrition may play an essential role in immunity by interfering with proinflammatory cytokine synthesis, immune cell regulation, and gene expression. Polyphenols, one of many categories of natural substances, exhibit a range of biological activities. Polyphenols promote immunity to foreign pathogens via various pathways. Different immune cells express multiple types of polyphenol receptors that recognise and allow cellular uptake of polyphenols, which subsequently activate signalling pathways to initiate immune responses. Furthermore, the polyphenols curcumin and epigallocatechin gallate can induce epigenetic changes in cells. In summary, polyphenols can be used to regulate intestinal mucosal immune responses, allergic diseases, and antitumour immunity. |
| format | Article |
| id | doaj-art-252572db7e2f476ba7fb16142fd8ebbf |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-252572db7e2f476ba7fb16142fd8ebbf2025-02-03T06:15:12ZengWileyJournal of Immunology Research2314-88612314-71562018-01-01201810.1155/2018/12640741264074Regulation of Immune Function by PolyphenolsSujuan Ding0Hongmei Jiang1Jun Fang2College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, ChinaCollege of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, ChinaCollege of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, ChinaImmune dysfunction is caused by various factors, including changes in relevant immune regulators and environmental stress. Immune system imbalance leads to a variety of diseases in humans. Nutrition may play an essential role in immunity by interfering with proinflammatory cytokine synthesis, immune cell regulation, and gene expression. Polyphenols, one of many categories of natural substances, exhibit a range of biological activities. Polyphenols promote immunity to foreign pathogens via various pathways. Different immune cells express multiple types of polyphenol receptors that recognise and allow cellular uptake of polyphenols, which subsequently activate signalling pathways to initiate immune responses. Furthermore, the polyphenols curcumin and epigallocatechin gallate can induce epigenetic changes in cells. In summary, polyphenols can be used to regulate intestinal mucosal immune responses, allergic diseases, and antitumour immunity.http://dx.doi.org/10.1155/2018/1264074 |
| spellingShingle | Sujuan Ding Hongmei Jiang Jun Fang Regulation of Immune Function by Polyphenols Journal of Immunology Research |
| title | Regulation of Immune Function by Polyphenols |
| title_full | Regulation of Immune Function by Polyphenols |
| title_fullStr | Regulation of Immune Function by Polyphenols |
| title_full_unstemmed | Regulation of Immune Function by Polyphenols |
| title_short | Regulation of Immune Function by Polyphenols |
| title_sort | regulation of immune function by polyphenols |
| url | http://dx.doi.org/10.1155/2018/1264074 |
| work_keys_str_mv | AT sujuanding regulationofimmunefunctionbypolyphenols AT hongmeijiang regulationofimmunefunctionbypolyphenols AT junfang regulationofimmunefunctionbypolyphenols |