A note on the use of influenza vaccination strategies when supply is limited
The 2009 A (H1N1) influenza pandemic was rather atypical. It began in North America at the start of the spring and in the following months, as it moved south, efforts to develop a vaccine that would mitigate the potential impact of a second wave were accelerated. The world's limited capacity...
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| Format: | Article |
| Language: | English |
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AIMS Press
2010-12-01
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| Series: | Mathematical Biosciences and Engineering |
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| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.171 |
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| author | Sunmi Lee Romarie Morales Carlos Castillo-Chavez |
| author_facet | Sunmi Lee Romarie Morales Carlos Castillo-Chavez |
| author_sort | Sunmi Lee |
| collection | DOAJ |
| description | The 2009 A (H1N1) influenza pandemic was rather atypical. It began in North America at the start of the spring and in the following months, as it moved south, efforts to develop a vaccine that would mitigate the potential impact of a second wave were accelerated. The world's limited capacity to produce an adequate vaccine supply over just a few months resulted in the development of public health policies that 'had' to optimize the utilization of limited vaccine supplies. Furthermore, even after the vaccine was in production, extensive delays in vaccine distribution were experienced for various reasons. In this note, we use optimal control theory to explore the impact of some of the constraints faced by most nations in implementing a public health policy that tried to meet the challenges that come from having access only to a limited vaccine supply that is never 100% effective. |
| format | Article |
| id | doaj-art-24f0ba665022448697492e72f9d5c9b2 |
| institution | Kabale University |
| issn | 1551-0018 |
| language | English |
| publishDate | 2010-12-01 |
| publisher | AIMS Press |
| record_format | Article |
| series | Mathematical Biosciences and Engineering |
| spelling | doaj-art-24f0ba665022448697492e72f9d5c9b22025-01-24T02:01:20ZengAIMS PressMathematical Biosciences and Engineering1551-00182010-12-018117118210.3934/mbe.2011.8.171A note on the use of influenza vaccination strategies when supply is limitedSunmi Lee0Romarie Morales1Carlos Castillo-Chavez2Mathematical, Computational and Modeling Sciences Center, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ 85287Mathematical, Computational and Modeling Sciences Center, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ 85287Mathematical, Computational and Modeling Sciences Center, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ 85287The 2009 A (H1N1) influenza pandemic was rather atypical. It began in North America at the start of the spring and in the following months, as it moved south, efforts to develop a vaccine that would mitigate the potential impact of a second wave were accelerated. The world's limited capacity to produce an adequate vaccine supply over just a few months resulted in the development of public health policies that 'had' to optimize the utilization of limited vaccine supplies. Furthermore, even after the vaccine was in production, extensive delays in vaccine distribution were experienced for various reasons. In this note, we use optimal control theory to explore the impact of some of the constraints faced by most nations in implementing a public health policy that tried to meet the challenges that come from having access only to a limited vaccine supply that is never 100% effective.https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.171optimal controlvaccineinfluenza pandemicisoperimetric constraint. |
| spellingShingle | Sunmi Lee Romarie Morales Carlos Castillo-Chavez A note on the use of influenza vaccination strategies when supply is limited Mathematical Biosciences and Engineering optimal control vaccine influenza pandemic isoperimetric constraint. |
| title | A note on the use of influenza vaccination strategies when supply is limited |
| title_full | A note on the use of influenza vaccination strategies when supply is limited |
| title_fullStr | A note on the use of influenza vaccination strategies when supply is limited |
| title_full_unstemmed | A note on the use of influenza vaccination strategies when supply is limited |
| title_short | A note on the use of influenza vaccination strategies when supply is limited |
| title_sort | note on the use of influenza vaccination strategies when supply is limited |
| topic | optimal control vaccine influenza pandemic isoperimetric constraint. |
| url | https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.171 |
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