Role of YAP/TAZ in bone diseases: A transductor from mechanics to biology

Wolff's Law and the Mechanostat Theory elucidate how bone tissues detect and convert mechanical stimuli into biological signals, crucial for maintaining bone equilibrium. Abnormal mechanics can lead to diseases such as osteoporosis, osteoarthritis, and nonunion fractures. However, the detailed...

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Bibliographic Details
Main Authors: Xin Chen, Xing Ji, Zhaobai Lao, Bin Pan, Yu Qian, Wanlei Yang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Orthopaedic Translation
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X24001633
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