Osteomyelitis Caused by Candida glabrata in the Distal Phalanx

Osteomyelitis caused by Candida glabrata is rare and its optimal treatment is unknown. Here we report a case of osteomyelitis caused by C. glabrata in the distal phalanx in a 54-year-old woman. Despite partial resection of the nail and administering a 1-month course of antibiotics for paronychia, th...

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Main Authors: Shunichi Toki, Naohito Hibino, Koichi Sairyo, Mitsuhiko Takahashi, Shinji Yoshioka, Masahiro Yamano, Tatsuhiko Henmi
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2014/962575
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author Shunichi Toki
Naohito Hibino
Koichi Sairyo
Mitsuhiko Takahashi
Shinji Yoshioka
Masahiro Yamano
Tatsuhiko Henmi
author_facet Shunichi Toki
Naohito Hibino
Koichi Sairyo
Mitsuhiko Takahashi
Shinji Yoshioka
Masahiro Yamano
Tatsuhiko Henmi
author_sort Shunichi Toki
collection DOAJ
description Osteomyelitis caused by Candida glabrata is rare and its optimal treatment is unknown. Here we report a case of osteomyelitis caused by C. glabrata in the distal phalanx in a 54-year-old woman. Despite partial resection of the nail and administering a 1-month course of antibiotics for paronychia, the local swelling remained and an osteolytic lesion was found. C. glabrata osteomyelitis of the distal phalanx was later diagnosed after curettage. Thereafter, the patient was treated with antifungal agents for 3 months. The infection eventually resolved, and radiological healing of the osteolytic lesion was achieved. Antifungal susceptibility testing should be performed in the case of osteomyelitis caused by nonalbicans Candida species, due to their resistance to fluconazole.
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publisher Wiley
record_format Article
series Case Reports in Orthopedics
spelling doaj-art-24b8a992e0fb4c91a1bfd9cbdf37462c2025-02-03T05:57:34ZengWileyCase Reports in Orthopedics2090-67492090-67572014-01-01201410.1155/2014/962575962575Osteomyelitis Caused by Candida glabrata in the Distal PhalanxShunichi Toki0Naohito Hibino1Koichi Sairyo2Mitsuhiko Takahashi3Shinji Yoshioka4Masahiro Yamano5Tatsuhiko Henmi6Tokushima Prefecture Naruto Hospital, 32 Kotani, Kurosaki, Muya-cho, Naruto-shi, Tokushima 772-8503, JapanTokushima Prefecture Naruto Hospital, 32 Kotani, Kurosaki, Muya-cho, Naruto-shi, Tokushima 772-8503, JapanTokushima Prefecture Naruto Hospital, 32 Kotani, Kurosaki, Muya-cho, Naruto-shi, Tokushima 772-8503, JapanTokushima Prefecture Naruto Hospital, 32 Kotani, Kurosaki, Muya-cho, Naruto-shi, Tokushima 772-8503, JapanTokushima Prefecture Naruto Hospital, 32 Kotani, Kurosaki, Muya-cho, Naruto-shi, Tokushima 772-8503, JapanTokushima Prefecture Naruto Hospital, 32 Kotani, Kurosaki, Muya-cho, Naruto-shi, Tokushima 772-8503, JapanTokushima Prefecture Naruto Hospital, 32 Kotani, Kurosaki, Muya-cho, Naruto-shi, Tokushima 772-8503, JapanOsteomyelitis caused by Candida glabrata is rare and its optimal treatment is unknown. Here we report a case of osteomyelitis caused by C. glabrata in the distal phalanx in a 54-year-old woman. Despite partial resection of the nail and administering a 1-month course of antibiotics for paronychia, the local swelling remained and an osteolytic lesion was found. C. glabrata osteomyelitis of the distal phalanx was later diagnosed after curettage. Thereafter, the patient was treated with antifungal agents for 3 months. The infection eventually resolved, and radiological healing of the osteolytic lesion was achieved. Antifungal susceptibility testing should be performed in the case of osteomyelitis caused by nonalbicans Candida species, due to their resistance to fluconazole.http://dx.doi.org/10.1155/2014/962575
spellingShingle Shunichi Toki
Naohito Hibino
Koichi Sairyo
Mitsuhiko Takahashi
Shinji Yoshioka
Masahiro Yamano
Tatsuhiko Henmi
Osteomyelitis Caused by Candida glabrata in the Distal Phalanx
Case Reports in Orthopedics
title Osteomyelitis Caused by Candida glabrata in the Distal Phalanx
title_full Osteomyelitis Caused by Candida glabrata in the Distal Phalanx
title_fullStr Osteomyelitis Caused by Candida glabrata in the Distal Phalanx
title_full_unstemmed Osteomyelitis Caused by Candida glabrata in the Distal Phalanx
title_short Osteomyelitis Caused by Candida glabrata in the Distal Phalanx
title_sort osteomyelitis caused by candida glabrata in the distal phalanx
url http://dx.doi.org/10.1155/2014/962575
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