Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report
Abstract Background Recurrent Non-Tuberculous Mycobacterial Pulmonary Disease (NTM-PD) related to treatment with Secukinumab has not been previously documented. Case presentation Despite adherence to treatment and avoiding hot springs, a plaque psoriasis patient experienced persistent NTM-PD relapse...
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| Format: | Article |
| Language: | English |
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BMC
2025-01-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-025-10487-4 |
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| author | Yixiao Wei Chunlei Wang Lingtao Chong Xiaojing Cui |
| author_facet | Yixiao Wei Chunlei Wang Lingtao Chong Xiaojing Cui |
| author_sort | Yixiao Wei |
| collection | DOAJ |
| description | Abstract Background Recurrent Non-Tuberculous Mycobacterial Pulmonary Disease (NTM-PD) related to treatment with Secukinumab has not been previously documented. Case presentation Despite adherence to treatment and avoiding hot springs, a plaque psoriasis patient experienced persistent NTM-PD relapses. Conclusions There is potential association between Secukinumab, an IL-17A inhibitor, and NTM disease, echoing anti-TNF biologics’ NTM risk, indicating the urgent need for further research on pathogenic mechanisms and risk factors. |
| format | Article |
| id | doaj-art-24b4f18232d742f7b26a3eb6102c4147 |
| institution | Kabale University |
| issn | 1471-2334 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj-art-24b4f18232d742f7b26a3eb6102c41472025-01-26T12:17:21ZengBMCBMC Infectious Diseases1471-23342025-01-012511510.1186/s12879-025-10487-4Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case reportYixiao Wei0Chunlei Wang1Lingtao Chong2Xiaojing Cui3Peking University Health Science CenterLaboratory of Clinical Microbiology and Infectious Diseases, China-Japan Friendship HospitalFuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical CollegeNational Clinical Research Center of Respiratory Diseases, Center for Respiratory Diseases, China-Japan Friendship HospitalAbstract Background Recurrent Non-Tuberculous Mycobacterial Pulmonary Disease (NTM-PD) related to treatment with Secukinumab has not been previously documented. Case presentation Despite adherence to treatment and avoiding hot springs, a plaque psoriasis patient experienced persistent NTM-PD relapses. Conclusions There is potential association between Secukinumab, an IL-17A inhibitor, and NTM disease, echoing anti-TNF biologics’ NTM risk, indicating the urgent need for further research on pathogenic mechanisms and risk factors.https://doi.org/10.1186/s12879-025-10487-4Nontuberculous mycobacteriaNTM-PDMycobacterium avium complexSecukinumabPsoriasis |
| spellingShingle | Yixiao Wei Chunlei Wang Lingtao Chong Xiaojing Cui Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report BMC Infectious Diseases Nontuberculous mycobacteria NTM-PD Mycobacterium avium complex Secukinumab Psoriasis |
| title | Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report |
| title_full | Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report |
| title_fullStr | Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report |
| title_full_unstemmed | Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report |
| title_short | Recurrent NTM pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with Secukinumab: a case report |
| title_sort | recurrent ntm pulmonary disease despite avoidance of hot spring exposure in a plaque psoriasis patient treated with secukinumab a case report |
| topic | Nontuberculous mycobacteria NTM-PD Mycobacterium avium complex Secukinumab Psoriasis |
| url | https://doi.org/10.1186/s12879-025-10487-4 |
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