IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia

This case presents a patient with bacteremia of an unusual organism with a history of monoclonal gammopathy of undetermined significance (MGUS). MGUS is typically thought to be asymptomatic until potential progression of the disease. This case reports a patient with a history of MGUS who does not sh...

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Main Authors: Jennifer Paterno, Alessandra Petrillo, David Samuel Dicapua Siegel, Chinwe Ogedegbe
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2020/8823908
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author Jennifer Paterno
Alessandra Petrillo
David Samuel Dicapua Siegel
Chinwe Ogedegbe
author_facet Jennifer Paterno
Alessandra Petrillo
David Samuel Dicapua Siegel
Chinwe Ogedegbe
author_sort Jennifer Paterno
collection DOAJ
description This case presents a patient with bacteremia of an unusual organism with a history of monoclonal gammopathy of undetermined significance (MGUS). MGUS is typically thought to be asymptomatic until potential progression of the disease. This case reports a patient with a history of MGUS who does not show disease progression, however, may be showing symptoms, such as immunodeficiency. This case displays bacteremia with Streptococcus mitis within a two-week period of an invasive procedure. Recent studies parallel this case by showing MGUS patients may have two times the risk of infections compared to the unaffected population. This report brings up the question of taking prophylactic measures for this patient population to prevent future complications.
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institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2020-01-01
publisher Wiley
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series Case Reports in Hematology
spelling doaj-art-24406ff64a304ed386d246c0ad35d8872025-02-03T01:28:09ZengWileyCase Reports in Hematology2090-65602090-65792020-01-01202010.1155/2020/88239088823908IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis BacteremiaJennifer Paterno0Alessandra Petrillo1David Samuel Dicapua Siegel2Chinwe Ogedegbe3Hackensack University Medical Center, 30 Prospect Ave, Hackensack, NJ, USAHackensack University Medical Center, 30 Prospect Ave, Hackensack, NJ, USAHackensack University Medical Center, 30 Prospect Ave, Hackensack, NJ, USAHackensack University Medical Center, 30 Prospect Ave, Hackensack, NJ, USAThis case presents a patient with bacteremia of an unusual organism with a history of monoclonal gammopathy of undetermined significance (MGUS). MGUS is typically thought to be asymptomatic until potential progression of the disease. This case reports a patient with a history of MGUS who does not show disease progression, however, may be showing symptoms, such as immunodeficiency. This case displays bacteremia with Streptococcus mitis within a two-week period of an invasive procedure. Recent studies parallel this case by showing MGUS patients may have two times the risk of infections compared to the unaffected population. This report brings up the question of taking prophylactic measures for this patient population to prevent future complications.http://dx.doi.org/10.1155/2020/8823908
spellingShingle Jennifer Paterno
Alessandra Petrillo
David Samuel Dicapua Siegel
Chinwe Ogedegbe
IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia
Case Reports in Hematology
title IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia
title_full IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia
title_fullStr IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia
title_full_unstemmed IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia
title_short IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia
title_sort iga monoclonal gammopathy of undetermined significance and complication of streptococcus mitis bacteremia
url http://dx.doi.org/10.1155/2020/8823908
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AT davidsamueldicapuasiegel igamonoclonalgammopathyofundeterminedsignificanceandcomplicationofstreptococcusmitisbacteremia
AT chinweogedegbe igamonoclonalgammopathyofundeterminedsignificanceandcomplicationofstreptococcusmitisbacteremia