Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development

Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development

Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are closely related diseases associated with smoking history and dysregulated immune response. However, not all smokers develop the disease, indicating that genetic susceptibility could be important. Therefore, the aim of this study w...

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Main Authors: Baranasic Jurica, Niazi Yasmeen, Chattopadhyay Subhayan, Rumora Lada, Ćorak Lorna, Dugac Andrea Vukić, Jakopović Marko, Samaržija Miroslav, Försti Asta, Knežević Jelena
Format: Article
Language:English
Published: Sciendo 2023-06-01
Series:Acta Pharmaceutica
Subjects:
gwas
snp
copd
lung cancer
immune-related genes
nf-κb
Online Access:https://doi.org/10.2478/acph-2023-0019
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