Feasibility of Ex Vivo Ligandomics
We developed ligandomics for the in vivo profiling of vascular ligands in mice, discovering secretogranin III (Scg3) as a novel angiogenic factor that selectively binds to retinal vessels of diabetic but not healthy mice. This discovery led to the development of anti-Scg3 therapy for ocular vasculop...
Saved in:
Main Authors: | Prabuddha Waduge, Remya Ammassam Veettil, Bojun Zhang, Chengchi Huang, Hong Tian, Wei Li |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-01-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/15/1/145 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol
by: Nada Aly H., et al.
Published: (2014-09-01) -
Ex vivo delivery of recombinant IL-10 to human donor lungs
by: Jonathan C. Yeung, et al.
Published: (2025-02-01) -
Advancing ex vivo functional whole-organ prostate gland model for regeneration and drug screening
by: Karthikeyan Subbiahanadar Chelladurai, et al.
Published: (2025-01-01) -
Impact of High Glucose on Bone Collagenous Matrix Composition, Structure, and Organization: An Integrative Analysis Using an Ex Vivo Model
by: Rita Araújo, et al.
Published: (2025-01-01) -
Association of Inflammatory Profile During Ex Vivo Lung Perfusion With High-Grade Primary Graft Dysfunction: A Systematic Review and Meta-Analysis
by: Andrea Costamagna, et al.
Published: (2025-01-01)