Quasi-Model-Based Control of Type 1 Diabetes Mellitus
Glucose-insulin models appeared in the literature are varying in complexity. Hence, their use in control theory is not trivial. The paper presents an optimal controller design framework to investigate the type 1 diabetes from control theory point of view. Starting from a recently published glucose-i...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Journal of Electrical and Computer Engineering |
| Online Access: | http://dx.doi.org/10.1155/2011/728540 |
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| Summary: | Glucose-insulin models appeared in the literature are varying in complexity. Hence,
their use in control theory is not trivial. The paper presents an optimal controller design
framework to investigate the type 1 diabetes from control theory point of view. Starting from
a recently published glucose-insulin model a Quasi Model with favorable control properties
is developed minimizing the physiological states to be taken into account. The purpose of the
Quasi Model is not to model the glucose-glucagon-insulin interaction precisely, but only to grasp the
characteristic behavior such that the designed controller can successfully regulate the unbalanced
system. Different optimal control strategies (pole-placement, LQ, Minimax control) are designed
on the Quasi Model, and the obtained controllers' applicability is investigated on two more
sophisticated type 1 diabetic models using two absorption scenarios. The developed framework
could help researchers engaging the control problem of diabetes. |
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| ISSN: | 2090-0147 2090-0155 |