Electrocatalytic detection of Acetaminophen by sodium ferrite
Acetaminophen (APN) is a safer alternative to opioids and is recognized for its analgesic and antipyretic properties. Prolonged usage and overdose of APN cause severe health problems for humans. Hence, its monitoring in the human body, pharmaceutical preparations and consumption sources is important...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Results in Physics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211379724007587 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832595740473425920 |
|---|---|
| author | Saima Perveen Jameel Ahmed Baig Mohammad Nur-e-Alam Mohsin Kazi Shahabuddin Memon Tasneem Gul Kazi Khalil Akhtar Sajjad Hussain |
| author_facet | Saima Perveen Jameel Ahmed Baig Mohammad Nur-e-Alam Mohsin Kazi Shahabuddin Memon Tasneem Gul Kazi Khalil Akhtar Sajjad Hussain |
| author_sort | Saima Perveen |
| collection | DOAJ |
| description | Acetaminophen (APN) is a safer alternative to opioids and is recognized for its analgesic and antipyretic properties. Prolonged usage and overdose of APN cause severe health problems for humans. Hence, its monitoring in the human body, pharmaceutical preparations and consumption sources is important. Thus, the current study was designed to synthesize the sodium ferrite nanoparticles (Na2Fe4O7-NPs) based on the Tamarindus indica fruit extract for selective trace electrochemical detection of APN. The Na2Fe4O7-NPs were characterized by advanced analytical techniques such as x-ray diffraction (XRD), fourier transform infrared (FTIR), UV–visible, atomic force microscopy (AFM), zeta potential, zeta sizer, energy dispersive x-ray (EDX) and field emission scanning electron microscopy (FESEM) which displayed that the Na2Fe4O7-NPs possess hexagonal structure, a narrow band gap (1.475 eV), corresponding to their excellent electronic capability, nanosize of particles, rough surface and highly stable nature for electrochemical analysis. Na2Fe4O7-NPs were deposited on a glassy carbon electrode (GCE) to manufacture an electrochemical sensor (Na2Fe4O7-NPs/GCE) and characterized its surface behaviour by cyclic voltammetry. Na2Fe4O7-NPs/GCE voltammetric sensor showed its selective sensing of APN in a wide dynamic range (1.0 × 10-8 to 4.5 × 10-4 M) with a detection limit of 2.72 10-9 M. Further, the developed method showed excellent stability in addition to reproducibility for the sensing of APN (% RSD < 5.0). The developed electrochemical sensor was found to be efficient for selective and sensitive detection of APN in real samples with quantitative recoveries (> 90 %). |
| format | Article |
| id | doaj-art-23edbfe35fe54641a34f42c82bc3c7ea |
| institution | Kabale University |
| issn | 2211-3797 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Physics |
| spelling | doaj-art-23edbfe35fe54641a34f42c82bc3c7ea2025-01-18T05:04:29ZengElsevierResults in Physics2211-37972025-01-0168108073Electrocatalytic detection of Acetaminophen by sodium ferriteSaima Perveen0Jameel Ahmed Baig1Mohammad Nur-e-Alam2Mohsin Kazi3Shahabuddin Memon4Tasneem Gul Kazi5Khalil Akhtar6Sajjad Hussain7Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan; Pamukkale University, Faculty of Science, Chemistry Department, Pamukkale, Denizli, TurkeyCentre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan; Corresponding author.Department of Pharmacognosy, College of Pharmacy, King Saud University, PO Box, 2457, Riyadh 11451, Saudi ArabiaDepartment of Pharmaceutics, College of Pharmacy, King Saud University, PO Box, 2457, Riyadh 11451, Saudi ArabiaCentre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, PakistanCentre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, PakistanCentre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, PakistanCentre of Excellence in Solid State Physics, University of the Punjab, Lahore, 05422, PakistanAcetaminophen (APN) is a safer alternative to opioids and is recognized for its analgesic and antipyretic properties. Prolonged usage and overdose of APN cause severe health problems for humans. Hence, its monitoring in the human body, pharmaceutical preparations and consumption sources is important. Thus, the current study was designed to synthesize the sodium ferrite nanoparticles (Na2Fe4O7-NPs) based on the Tamarindus indica fruit extract for selective trace electrochemical detection of APN. The Na2Fe4O7-NPs were characterized by advanced analytical techniques such as x-ray diffraction (XRD), fourier transform infrared (FTIR), UV–visible, atomic force microscopy (AFM), zeta potential, zeta sizer, energy dispersive x-ray (EDX) and field emission scanning electron microscopy (FESEM) which displayed that the Na2Fe4O7-NPs possess hexagonal structure, a narrow band gap (1.475 eV), corresponding to their excellent electronic capability, nanosize of particles, rough surface and highly stable nature for electrochemical analysis. Na2Fe4O7-NPs were deposited on a glassy carbon electrode (GCE) to manufacture an electrochemical sensor (Na2Fe4O7-NPs/GCE) and characterized its surface behaviour by cyclic voltammetry. Na2Fe4O7-NPs/GCE voltammetric sensor showed its selective sensing of APN in a wide dynamic range (1.0 × 10-8 to 4.5 × 10-4 M) with a detection limit of 2.72 10-9 M. Further, the developed method showed excellent stability in addition to reproducibility for the sensing of APN (% RSD < 5.0). The developed electrochemical sensor was found to be efficient for selective and sensitive detection of APN in real samples with quantitative recoveries (> 90 %).http://www.sciencedirect.com/science/article/pii/S2211379724007587Electrochemical analysis, sodium ferrite nanoparticlesDifferential pulse voltammetryGlassy carbon electrodeAcetaminophen |
| spellingShingle | Saima Perveen Jameel Ahmed Baig Mohammad Nur-e-Alam Mohsin Kazi Shahabuddin Memon Tasneem Gul Kazi Khalil Akhtar Sajjad Hussain Electrocatalytic detection of Acetaminophen by sodium ferrite Results in Physics Electrochemical analysis, sodium ferrite nanoparticles Differential pulse voltammetry Glassy carbon electrode Acetaminophen |
| title | Electrocatalytic detection of Acetaminophen by sodium ferrite |
| title_full | Electrocatalytic detection of Acetaminophen by sodium ferrite |
| title_fullStr | Electrocatalytic detection of Acetaminophen by sodium ferrite |
| title_full_unstemmed | Electrocatalytic detection of Acetaminophen by sodium ferrite |
| title_short | Electrocatalytic detection of Acetaminophen by sodium ferrite |
| title_sort | electrocatalytic detection of acetaminophen by sodium ferrite |
| topic | Electrochemical analysis, sodium ferrite nanoparticles Differential pulse voltammetry Glassy carbon electrode Acetaminophen |
| url | http://www.sciencedirect.com/science/article/pii/S2211379724007587 |
| work_keys_str_mv | AT saimaperveen electrocatalyticdetectionofacetaminophenbysodiumferrite AT jameelahmedbaig electrocatalyticdetectionofacetaminophenbysodiumferrite AT mohammadnurealam electrocatalyticdetectionofacetaminophenbysodiumferrite AT mohsinkazi electrocatalyticdetectionofacetaminophenbysodiumferrite AT shahabuddinmemon electrocatalyticdetectionofacetaminophenbysodiumferrite AT tasneemgulkazi electrocatalyticdetectionofacetaminophenbysodiumferrite AT khalilakhtar electrocatalyticdetectionofacetaminophenbysodiumferrite AT sajjadhussain electrocatalyticdetectionofacetaminophenbysodiumferrite |