A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus
A 73-year-old woman admitted to our hospital because of headache, poor appetite, malaise, weight loss, and vomiting was found to have central adrenal insufficiency and thyrotoxicosis due to silent thyroiditis. Polyuria developed after replacement with glucocorticoid (masked diabetes insipidus), whic...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/693294 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832551097873465344 |
|---|---|
| author | Masahiro Asakawa Rina Chin Yoshihiro Niitsu Tetsuo Sekine Arisa Niwa Atsuko Miyake Naoko Inoshita Mitsunobu Kawamura Yoshihiro Ogawa Yukio Hirata |
| author_facet | Masahiro Asakawa Rina Chin Yoshihiro Niitsu Tetsuo Sekine Arisa Niwa Atsuko Miyake Naoko Inoshita Mitsunobu Kawamura Yoshihiro Ogawa Yukio Hirata |
| author_sort | Masahiro Asakawa |
| collection | DOAJ |
| description | A 73-year-old woman admitted to our hospital because of headache, poor appetite, malaise, weight loss, and vomiting was found to have central adrenal insufficiency and thyrotoxicosis due to silent thyroiditis. Polyuria developed after replacement with glucocorticoid (masked diabetes insipidus), which was controlled with nasal administration of desmopressin. Magnetic resonance imaging of the brain showed a large cystic pituitary mass (18 × 18 × 12 mm) extending suprasellarly to the optic chiasm. Transsphenoidal surgery revealed that the pituitary tumor was Rathke’s cleft cyst. Following surgery, replacement with neither glucocorticoid nor desmopressin was needed any more. Therefore, it is suggested that Rathke’s cleft cyst is responsible for the masked diabetes insipidus and the central insufficiency. Furthermore, it is speculated that thyrotoxicosis with painless thyroiditis might induce changes from subclinical adrenal insufficiency to transiently overt insufficiency. |
| format | Article |
| id | doaj-art-23ce0340b2ee4aedb58825a7a1db17a3 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-23ce0340b2ee4aedb58825a7a1db17a32025-02-03T06:04:58ZengWileyCase Reports in Endocrinology2090-65012090-651X2014-01-01201410.1155/2014/693294693294A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes InsipidusMasahiro Asakawa0Rina Chin1Yoshihiro Niitsu2Tetsuo Sekine3Arisa Niwa4Atsuko Miyake5Naoko Inoshita6Mitsunobu Kawamura7Yoshihiro Ogawa8Yukio Hirata9Department of Endocrinology and Metabolism, Tokyo Teishin Hospital, 2-14-23, Fujimi, Chiyoda-ku, Tokyo 102-0071, JapanDepartment of Endocrinology and Metabolism, Tokyo Kyosai Hospital, 2-3-8, Nakameguro, Meguro-ku, Tokyo 153-0061, JapanDepartment of Endocrinology and Metabolism, Tokyo Teishin Hospital, 2-14-23, Fujimi, Chiyoda-ku, Tokyo 102-0071, JapanDepartment of Endocrinology and Metabolism, Tokyo Teishin Hospital, 2-14-23, Fujimi, Chiyoda-ku, Tokyo 102-0071, JapanDepartment of Endocrinology and Metabolism, Tokyo Teishin Hospital, 2-14-23, Fujimi, Chiyoda-ku, Tokyo 102-0071, JapanDepartment of Endocrinology and Metabolism, Tokyo Teishin Hospital, 2-14-23, Fujimi, Chiyoda-ku, Tokyo 102-0071, JapanDepartment of Pathology, Toranomon Hospital, 2-2-2, Toranomon, Minato-ku, Tokyo 105-0001, JapanDepartment of Endocrinology and Metabolism, Tokyo Teishin Hospital, 2-14-23, Fujimi, Chiyoda-ku, Tokyo 102-0071, JapanDepartment of Molecular Endocrinology and Metabolism, Tokyo Medical and Dental University Hospital, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, JapanInstitute of Biochemical Research and Innovation Hospital, 2-2 Minatoshima-Minamicho, Chuo-ku, Kobe, Hyogo 650-0047, JapanA 73-year-old woman admitted to our hospital because of headache, poor appetite, malaise, weight loss, and vomiting was found to have central adrenal insufficiency and thyrotoxicosis due to silent thyroiditis. Polyuria developed after replacement with glucocorticoid (masked diabetes insipidus), which was controlled with nasal administration of desmopressin. Magnetic resonance imaging of the brain showed a large cystic pituitary mass (18 × 18 × 12 mm) extending suprasellarly to the optic chiasm. Transsphenoidal surgery revealed that the pituitary tumor was Rathke’s cleft cyst. Following surgery, replacement with neither glucocorticoid nor desmopressin was needed any more. Therefore, it is suggested that Rathke’s cleft cyst is responsible for the masked diabetes insipidus and the central insufficiency. Furthermore, it is speculated that thyrotoxicosis with painless thyroiditis might induce changes from subclinical adrenal insufficiency to transiently overt insufficiency.http://dx.doi.org/10.1155/2014/693294 |
| spellingShingle | Masahiro Asakawa Rina Chin Yoshihiro Niitsu Tetsuo Sekine Arisa Niwa Atsuko Miyake Naoko Inoshita Mitsunobu Kawamura Yoshihiro Ogawa Yukio Hirata A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus Case Reports in Endocrinology |
| title | A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus |
| title_full | A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus |
| title_fullStr | A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus |
| title_full_unstemmed | A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus |
| title_short | A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus |
| title_sort | case of rathke s cleft cyst associated with transient central adrenal insufficiency and masked diabetes insipidus |
| url | http://dx.doi.org/10.1155/2014/693294 |
| work_keys_str_mv | AT masahiroasakawa acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT rinachin acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT yoshihironiitsu acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT tetsuosekine acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT arisaniwa acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT atsukomiyake acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT naokoinoshita acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT mitsunobukawamura acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT yoshihiroogawa acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT yukiohirata acaseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT masahiroasakawa caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT rinachin caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT yoshihironiitsu caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT tetsuosekine caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT arisaniwa caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT atsukomiyake caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT naokoinoshita caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT mitsunobukawamura caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT yoshihiroogawa caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus AT yukiohirata caseofrathkescleftcystassociatedwithtransientcentraladrenalinsufficiencyandmaskeddiabetesinsipidus |