A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis

This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal...

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Main Authors: Alison Markland, Gregory Hansen, Anke Banks, Rajni Chibbar, Darryl Adamko
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2017/1050284
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author Alison Markland
Gregory Hansen
Anke Banks
Rajni Chibbar
Darryl Adamko
author_facet Alison Markland
Gregory Hansen
Anke Banks
Rajni Chibbar
Darryl Adamko
author_sort Alison Markland
collection DOAJ
description This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. This may be an interesting avenue of exploration going forward given the lack of evidence in treating such conditions and emergence of CRRT.
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institution Kabale University
issn 2090-6420
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language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Critical Care
spelling doaj-art-23c8190ec72e4c688a1463d0e12c2ee52025-02-03T05:51:02ZengWileyCase Reports in Critical Care2090-64202090-64392017-01-01201710.1155/2017/10502841050284A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal GlomerulonephritisAlison Markland0Gregory Hansen1Anke Banks2Rajni Chibbar3Darryl Adamko4University of Saskatchewan, Saskatoon, SK, CanadaDivision of Pediatric Intensive Care, University of Saskatchewan, Saskatoon, SK, CanadaDepartment of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, CanadaDepartment of Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, CanadaDivision of Pediatric Respirology, University of Saskatchewan, Saskatoon, SK, CanadaThis report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. This may be an interesting avenue of exploration going forward given the lack of evidence in treating such conditions and emergence of CRRT.http://dx.doi.org/10.1155/2017/1050284
spellingShingle Alison Markland
Gregory Hansen
Anke Banks
Rajni Chibbar
Darryl Adamko
A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
Case Reports in Critical Care
title A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_full A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_fullStr A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_full_unstemmed A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_short A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_sort pediatric case of diffuse alveolar hemorrhage secondary to poststreptococcal glomerulonephritis
url http://dx.doi.org/10.1155/2017/1050284
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