Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation
Introduction. The prevalence of coronary artery disease (CAD) detected in preoperative work-up for transcatheter aortic valve implantation (TAVI) is high. Instead, the management of a concomitant CAD remains unclear. We evaluate the impact of CAD and percutaneous coronary intervention (PCI) on TAVI...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Interventional Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2021/6672400 |
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| author | Anthony G. Matta Thibault Lhermusier Francisco Campelo Parada Frederic Bouisset Ronan Canitrot Vanessa Nader Stéphanie Blanco Meyer Elbaz Jerome Roncalli Didier Carrié |
| author_facet | Anthony G. Matta Thibault Lhermusier Francisco Campelo Parada Frederic Bouisset Ronan Canitrot Vanessa Nader Stéphanie Blanco Meyer Elbaz Jerome Roncalli Didier Carrié |
| author_sort | Anthony G. Matta |
| collection | DOAJ |
| description | Introduction. The prevalence of coronary artery disease (CAD) detected in preoperative work-up for transcatheter aortic valve implantation (TAVI) is high. Instead, the management of a concomitant CAD remains unclear. We evaluate the impact of CAD and percutaneous coronary intervention (PCI) on TAVI procedures. Materials and Methods. A retrospective study was conducted on 1336 consecutive patients who underwent TAVI in Toulouse University Hospital, Rangueil, France. The studied population was divided into 2 groups: CAD-TAVI group and No CAD-TAVI group. Then, the CAD-TAVI group was segregated into 2 subgroups: PCI-TAVI group and No PCI-TAVI group. In-hospital adverse clinical outcomes were assessed in each group. Results. Pre-TAVI work-up revealed significant CAD in 36% of 1030 patients eligible for inclusion in the study. The overall prevalence of in-hospital death, stroke, major or life-threatening bleeding, minor bleeding, major vascular complications, minor vascular complications, pacemaker implantation, and acute kidney injury was 2.7%, 2.4%, 2.8%, 3.6%, 3.9%, 7.5%, 12.5%, and 2.7%, respectively. Among the studied population, 55% were admitted to the cardiac care unit. No significant statistical difference was observed between groups. Discussion. CAD-TAVI population was not more likely to develop in-hospital adverse clinical outcomes post-TAVI procedure compared to others. Also, no significant difference regarding in-hospital death was observed. In parallel, performing PCI prior to TAVI did not increase the risk of in-hospital death and complications. The difference in terms of the distribution of antithrombotic regimen may explain the higher prevalence of bleeding events in the PCI-TAVI group. Conclusion. This study provides direct clinical relevance useful in daily practice. No negative impact has been attributed to the presence of a concomitant CAD and/or preoperative PCI on the TAVI hospitalization period. |
| format | Article |
| id | doaj-art-23a0c6a875b04da3baf354558141f82d |
| institution | Kabale University |
| issn | 0896-4327 1540-8183 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Interventional Cardiology |
| spelling | doaj-art-23a0c6a875b04da3baf354558141f82d2025-02-03T06:05:27ZengWileyJournal of Interventional Cardiology0896-43271540-81832021-01-01202110.1155/2021/66724006672400Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve ImplantationAnthony G. Matta0Thibault Lhermusier1Francisco Campelo Parada2Frederic Bouisset3Ronan Canitrot4Vanessa Nader5Stéphanie Blanco6Meyer Elbaz7Jerome Roncalli8Didier Carrié9Department of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceDepartment of Cardiology, Rangueil University Hospital, Toulouse, FranceIntroduction. The prevalence of coronary artery disease (CAD) detected in preoperative work-up for transcatheter aortic valve implantation (TAVI) is high. Instead, the management of a concomitant CAD remains unclear. We evaluate the impact of CAD and percutaneous coronary intervention (PCI) on TAVI procedures. Materials and Methods. A retrospective study was conducted on 1336 consecutive patients who underwent TAVI in Toulouse University Hospital, Rangueil, France. The studied population was divided into 2 groups: CAD-TAVI group and No CAD-TAVI group. Then, the CAD-TAVI group was segregated into 2 subgroups: PCI-TAVI group and No PCI-TAVI group. In-hospital adverse clinical outcomes were assessed in each group. Results. Pre-TAVI work-up revealed significant CAD in 36% of 1030 patients eligible for inclusion in the study. The overall prevalence of in-hospital death, stroke, major or life-threatening bleeding, minor bleeding, major vascular complications, minor vascular complications, pacemaker implantation, and acute kidney injury was 2.7%, 2.4%, 2.8%, 3.6%, 3.9%, 7.5%, 12.5%, and 2.7%, respectively. Among the studied population, 55% were admitted to the cardiac care unit. No significant statistical difference was observed between groups. Discussion. CAD-TAVI population was not more likely to develop in-hospital adverse clinical outcomes post-TAVI procedure compared to others. Also, no significant difference regarding in-hospital death was observed. In parallel, performing PCI prior to TAVI did not increase the risk of in-hospital death and complications. The difference in terms of the distribution of antithrombotic regimen may explain the higher prevalence of bleeding events in the PCI-TAVI group. Conclusion. This study provides direct clinical relevance useful in daily practice. No negative impact has been attributed to the presence of a concomitant CAD and/or preoperative PCI on the TAVI hospitalization period.http://dx.doi.org/10.1155/2021/6672400 |
| spellingShingle | Anthony G. Matta Thibault Lhermusier Francisco Campelo Parada Frederic Bouisset Ronan Canitrot Vanessa Nader Stéphanie Blanco Meyer Elbaz Jerome Roncalli Didier Carrié Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation Journal of Interventional Cardiology |
| title | Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation |
| title_full | Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation |
| title_fullStr | Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation |
| title_full_unstemmed | Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation |
| title_short | Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation |
| title_sort | impact of coronary artery disease and percutaneous coronary intervention on transcatheter aortic valve implantation |
| url | http://dx.doi.org/10.1155/2021/6672400 |
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