Early life stress and altered social behaviors: A perspective across species
Childhood and adolescent affiliations guide how individuals engage in social relationships throughout their lifetime and adverse experiences can promote biological alterations that facilitate behavioral maladaptation. Indeed, childhood victims of abuse are more likely to be diagnosed with conduct or...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Neuroscience Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0168010223002006 |
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| author | Lyonna F. Parise C. Joseph Burnett Scott J. Russo |
| author_facet | Lyonna F. Parise C. Joseph Burnett Scott J. Russo |
| author_sort | Lyonna F. Parise |
| collection | DOAJ |
| description | Childhood and adolescent affiliations guide how individuals engage in social relationships throughout their lifetime and adverse experiences can promote biological alterations that facilitate behavioral maladaptation. Indeed, childhood victims of abuse are more likely to be diagnosed with conduct or mood disorders which are both characterized by altered social engagement. A key domain particularly deserving of attention is aggressive behavior, a hallmark of many disorders characterized by deficits in reward processing. Animal models have been integral in identifying both the short- and long-term consequences of stress exposure and suggest that whether it is disruption to parental care or social isolation, chronic exposure to early life stress increases corticosterone, changes the expression of neurotransmitters and neuromodulators, and facilitates structural alterations to the hypothalamus, hippocampus, and amygdala, influencing how these brain regions communicate with other reward-related substrates. Herein, we describe how adverse early life experiences influence social behavioral outcomes across a wide range of species and highlight the long-term biological mechanisms that are most relevant to maladaptive aggressive behavior. |
| format | Article |
| id | doaj-art-23970dc3c7b745a98bd4f9139315cedb |
| institution | Kabale University |
| issn | 0168-0102 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Neuroscience Research |
| spelling | doaj-art-23970dc3c7b745a98bd4f9139315cedb2025-02-06T05:11:00ZengElsevierNeuroscience Research0168-01022025-02-012116574Early life stress and altered social behaviors: A perspective across speciesLyonna F. Parise0C. Joseph Burnett1Scott J. Russo2Corresponding authors.; Icahn School of Medicine, Nash Family Department of Neuroscience and Friedman Brain Institute, New York, NY, USAIcahn School of Medicine, Nash Family Department of Neuroscience and Friedman Brain Institute, New York, NY, USACorresponding authors.; Icahn School of Medicine, Nash Family Department of Neuroscience and Friedman Brain Institute, New York, NY, USAChildhood and adolescent affiliations guide how individuals engage in social relationships throughout their lifetime and adverse experiences can promote biological alterations that facilitate behavioral maladaptation. Indeed, childhood victims of abuse are more likely to be diagnosed with conduct or mood disorders which are both characterized by altered social engagement. A key domain particularly deserving of attention is aggressive behavior, a hallmark of many disorders characterized by deficits in reward processing. Animal models have been integral in identifying both the short- and long-term consequences of stress exposure and suggest that whether it is disruption to parental care or social isolation, chronic exposure to early life stress increases corticosterone, changes the expression of neurotransmitters and neuromodulators, and facilitates structural alterations to the hypothalamus, hippocampus, and amygdala, influencing how these brain regions communicate with other reward-related substrates. Herein, we describe how adverse early life experiences influence social behavioral outcomes across a wide range of species and highlight the long-term biological mechanisms that are most relevant to maladaptive aggressive behavior.http://www.sciencedirect.com/science/article/pii/S0168010223002006Early life stressSocial behaviorAggressionStress |
| spellingShingle | Lyonna F. Parise C. Joseph Burnett Scott J. Russo Early life stress and altered social behaviors: A perspective across species Neuroscience Research Early life stress Social behavior Aggression Stress |
| title | Early life stress and altered social behaviors: A perspective across species |
| title_full | Early life stress and altered social behaviors: A perspective across species |
| title_fullStr | Early life stress and altered social behaviors: A perspective across species |
| title_full_unstemmed | Early life stress and altered social behaviors: A perspective across species |
| title_short | Early life stress and altered social behaviors: A perspective across species |
| title_sort | early life stress and altered social behaviors a perspective across species |
| topic | Early life stress Social behavior Aggression Stress |
| url | http://www.sciencedirect.com/science/article/pii/S0168010223002006 |
| work_keys_str_mv | AT lyonnafparise earlylifestressandalteredsocialbehaviorsaperspectiveacrossspecies AT cjosephburnett earlylifestressandalteredsocialbehaviorsaperspectiveacrossspecies AT scottjrusso earlylifestressandalteredsocialbehaviorsaperspectiveacrossspecies |