Pilaralisib inhibits the replication of enteroviruses by targeting the PI3K/AKT signaling pathway
Abstract Enterovirus 71 (EV71) is a significant pathogen responsible for hand, foot, and mouth disease (HFMD), which poses a substantial public health concern, particularly in the Asia-Pacific region. The virus is transmitted primarily through the fecal-oral route and via respiratory droplets, enter...
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| Main Authors: | Jie Zhou, Yanping Wang, Guangyan Zhu, Mingzhe Yan, Zhengnan Li, Lin Li, Jingwen Kuang, Wenyuan Zhang, Chaolin Huang, Fuli Ren, Qingyu Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Virology Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12985-025-02881-w |
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