Interleukin‐1 Signaling on Vascular Smooth Muscle Cells Accelerates Atherosclerosis in a Murine Model of Kawasaki Disease

Interleukin‐1 Signaling on Vascular Smooth Muscle Cells Accelerates Atherosclerosis in a Murine Model of Kawasaki Disease

Background We previously showed that Lactobacillus casei cell wall extract‐induced Kawasaki disease (KD) vasculitis significantly accelerates atherosclerosis in hypercholesterolemic mice on high‐fat diet. Here, we investigated the contribution of IL‐1 (interleukin‐1) signaling on vascular smooth mus...

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Bibliographic Details
Main Authors: Shuang Chen, Asli Savas, Asli Atici, Youngho Lee, Malcolm Lane, Emily Aubuchon, Debbie Moreira, Alexander Hsu‐Wilbraham, Kenichi Shimada, Timothy R. Crother, Magali Noval Rivas, Moshe Arditi
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
interleukin‐1
Kawasaki disease
vascular smooth muscle cell
vasculitis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.040687
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