CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis
This study aims to investigate the role and mechanism of p-hydroxyl cinnamaldehyde (CMSP) in triggering ferroptosis of small cell lung cancer (SCLC) cells.
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-01-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2024-1100 |
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| _version_ | 1832593598730731520 |
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| author | Yan Xi Niu Yinghao Wang Yaojie Wei Sisi Han Lina Guo Zhongyu Zhao Lianmei Gao Feng |
| author_facet | Yan Xi Niu Yinghao Wang Yaojie Wei Sisi Han Lina Guo Zhongyu Zhao Lianmei Gao Feng |
| author_sort | Yan Xi |
| collection | DOAJ |
| description | This study aims to investigate the role and mechanism of p-hydroxyl cinnamaldehyde (CMSP) in triggering ferroptosis of small cell lung cancer (SCLC) cells. |
| format | Article |
| id | doaj-art-2367d1681ad549cea523407f47681a1e |
| institution | Kabale University |
| issn | 2391-5463 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj-art-2367d1681ad549cea523407f47681a1e2025-01-20T11:09:04ZengDe GruyterOpen Medicine2391-54632025-01-012011119320510.1515/med-2024-1100CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosisYan Xi0Niu Yinghao1Wang Yaojie2Wei Sisi3Han Lina4Guo Zhongyu5Zhao Lianmei6Gao Feng7Department of Clinical Laboratory, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, ChinaDepartment of Clinical Biobank, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, ChinaResearch Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, ChinaResearch Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, ChinaResearch Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, ChinaDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, ChinaResearch Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, ChinaDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, ChinaThis study aims to investigate the role and mechanism of p-hydroxyl cinnamaldehyde (CMSP) in triggering ferroptosis of small cell lung cancer (SCLC) cells.https://doi.org/10.1515/med-2024-1100p-hydroxyl cinnamaldehyde, cmspsclcmitochondrial dysfunctionferroptosishmox1 |
| spellingShingle | Yan Xi Niu Yinghao Wang Yaojie Wei Sisi Han Lina Guo Zhongyu Zhao Lianmei Gao Feng CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis Open Medicine p-hydroxyl cinnamaldehyde, cmsp sclc mitochondrial dysfunction ferroptosis hmox1 |
| title | CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis |
| title_full | CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis |
| title_fullStr | CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis |
| title_full_unstemmed | CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis |
| title_short | CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis |
| title_sort | cmsp exerts anti tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis |
| topic | p-hydroxyl cinnamaldehyde, cmsp sclc mitochondrial dysfunction ferroptosis hmox1 |
| url | https://doi.org/10.1515/med-2024-1100 |
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