Renal Leiomyosarcoma: A Diagnostic Challenge
Renal leiomyosarcoma is a very rare tumor that clinically and radiographically mimics more common renal malignancies. The infrequency of the condition makes it very difficult to diagnose. A 70-year-old male smoker presented with months of hematuria, right-sided flank pain, and weight loss. Imaging r...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/459282 |
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| author | Jose R. Valery Winston Tan Cherise Cortese |
| author_facet | Jose R. Valery Winston Tan Cherise Cortese |
| author_sort | Jose R. Valery |
| collection | DOAJ |
| description | Renal leiomyosarcoma is a very rare tumor that clinically and radiographically mimics more common renal malignancies. The infrequency of the condition makes it very difficult to diagnose. A 70-year-old male smoker presented with months of hematuria, right-sided flank pain, and weight loss. Imaging revealed a 3.8-centimeter renal mass that had characteristics similar to renal cell carcinoma. Initial biopsy of the mass was negative for malignancy. Two months later, subsequent imaging revealed what appeared to be metastatic bone lesions. Again, a biopsy of one of the lesions was negative for malignancy. Subsequent ureteral pyeloscopy, ureteroscopic renal pelvis biopsy, and brush cytology were negative for malignancy as well. The decision was made to perform nephrectomy for the removal of the mass. Pathologic analysis revealed renal leiomyosarcoma. This case illustrates the difficulty in diagnosing renal leiomyosarcoma. Repeated pathologic sampling was negative because of the tumor heterogeneity. Prompt diagnosis and treatment are very significant as surgical resection at an early stage offers the best prognosis. |
| format | Article |
| id | doaj-art-2362d3cb2d3b48199aee73a70d9aed64 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-2362d3cb2d3b48199aee73a70d9aed642025-02-03T06:42:08ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/459282459282Renal Leiomyosarcoma: A Diagnostic ChallengeJose R. Valery0Winston Tan1Cherise Cortese2Community Internal Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USAHematology/Oncology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USALaboratory Medicine and Pathology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USARenal leiomyosarcoma is a very rare tumor that clinically and radiographically mimics more common renal malignancies. The infrequency of the condition makes it very difficult to diagnose. A 70-year-old male smoker presented with months of hematuria, right-sided flank pain, and weight loss. Imaging revealed a 3.8-centimeter renal mass that had characteristics similar to renal cell carcinoma. Initial biopsy of the mass was negative for malignancy. Two months later, subsequent imaging revealed what appeared to be metastatic bone lesions. Again, a biopsy of one of the lesions was negative for malignancy. Subsequent ureteral pyeloscopy, ureteroscopic renal pelvis biopsy, and brush cytology were negative for malignancy as well. The decision was made to perform nephrectomy for the removal of the mass. Pathologic analysis revealed renal leiomyosarcoma. This case illustrates the difficulty in diagnosing renal leiomyosarcoma. Repeated pathologic sampling was negative because of the tumor heterogeneity. Prompt diagnosis and treatment are very significant as surgical resection at an early stage offers the best prognosis.http://dx.doi.org/10.1155/2013/459282 |
| spellingShingle | Jose R. Valery Winston Tan Cherise Cortese Renal Leiomyosarcoma: A Diagnostic Challenge Case Reports in Oncological Medicine |
| title | Renal Leiomyosarcoma: A Diagnostic Challenge |
| title_full | Renal Leiomyosarcoma: A Diagnostic Challenge |
| title_fullStr | Renal Leiomyosarcoma: A Diagnostic Challenge |
| title_full_unstemmed | Renal Leiomyosarcoma: A Diagnostic Challenge |
| title_short | Renal Leiomyosarcoma: A Diagnostic Challenge |
| title_sort | renal leiomyosarcoma a diagnostic challenge |
| url | http://dx.doi.org/10.1155/2013/459282 |
| work_keys_str_mv | AT joservalery renalleiomyosarcomaadiagnosticchallenge AT winstontan renalleiomyosarcomaadiagnosticchallenge AT cherisecortese renalleiomyosarcomaadiagnosticchallenge |