Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus
Direct conversion of human somatic cells to induced neurons (iNs), using lineage-specific transcription factors has opened new opportunities for cell therapy in a number of neurological diseases, including epilepsy. In most severe cases of epilepsy, seizures often originate in the hippocampus, where...
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Main Authors: | Natalia Avaliani, Ulrich Pfisterer, Andreas Heuer, Malin Parmar, Merab Kokaia, My Andersson |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
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Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2017/5718608 |
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