M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b

Amyotrophic lateral sclerosis (ALS) is a most frequently occurring and severe form of motor neuron disease, causing death within 3–5 years from diagnosis and with a worldwide incidence of about 2 per 100,000 person-years. Mutations in over twenty genes associated with familial forms of ALS have prov...

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Bibliographic Details
Main Authors: Chiara Parisi, Giulia Napoli, Pablo Pelegrin, Cinzia Volonté
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/2989548
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