A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomes

Knee osteoarthritis (KOA)is a degenerative joint condition affecting about 240 million people worldwide with rising incidences in India. The progressive nature of the disease leads to pain, reduced mobility, and diminished quality of life. Despite extensive global research, there is a lack of normat...

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Main Authors: Dias Tina Thomas, Charu Eapen, Atmananda S. Hegde, Prajwal Prabhudev Mane, Ajit R. Mahale
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:MethodsX
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Online Access:http://www.sciencedirect.com/science/article/pii/S2215016125000275
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author Dias Tina Thomas
Charu Eapen
Atmananda S. Hegde
Prajwal Prabhudev Mane
Ajit R. Mahale
author_facet Dias Tina Thomas
Charu Eapen
Atmananda S. Hegde
Prajwal Prabhudev Mane
Ajit R. Mahale
author_sort Dias Tina Thomas
collection DOAJ
description Knee osteoarthritis (KOA)is a degenerative joint condition affecting about 240 million people worldwide with rising incidences in India. The progressive nature of the disease leads to pain, reduced mobility, and diminished quality of life. Despite extensive global research, there is a lack of normative data on the cartilage thickness specific to the Indian population, which is crucial to understanding the nature of the disease progression. Thereby this study aims to establish normative cartilage thickness values in healthy Indian adults and correlate these values to the knee injury and osteoarthritis outcome score (KOOS). Using ultrasonography, the cartilage thickness will be measured in 100 healthy individuals. Baseline cartilage values will be linked to the various domains of the KOOS score to evaluate early cartilage degeneration and its impact on function. This research will address the gap in Indian-specific data, including early detection and management of KOA and improving clinical decision-making for better outcomes and quality of life. • Establish normative knee cartilage thickness in healthy Indian population using USG. • Helps identify KOA in early stages through USG-based cartilage thickness evaluation • Enables clinicians to target rehabilitation efforts effectively and potentially improve patients' outcomes and quality of life.
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spelling doaj-art-233238d050f1457092564b332fe06ada2025-01-27T04:21:59ZengElsevierMethodsX2215-01612025-06-0114103179A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomesDias Tina Thomas0Charu Eapen1Atmananda S. Hegde2Prajwal Prabhudev Mane3Ajit R. Mahale4Department of Physiotherapy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, Manipal, 576104, IndiaDepartment of Physiotherapy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, Manipal, 576104, India; Corresponding author at: Professor Department of Physiotherapy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India.Department of Orthopedics, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, Manipal, 576104, IndiaDepartment of Orthopedics, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, Manipal, 576104, IndiaDepartment of Radiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, Manipal, 576104, IndiaKnee osteoarthritis (KOA)is a degenerative joint condition affecting about 240 million people worldwide with rising incidences in India. The progressive nature of the disease leads to pain, reduced mobility, and diminished quality of life. Despite extensive global research, there is a lack of normative data on the cartilage thickness specific to the Indian population, which is crucial to understanding the nature of the disease progression. Thereby this study aims to establish normative cartilage thickness values in healthy Indian adults and correlate these values to the knee injury and osteoarthritis outcome score (KOOS). Using ultrasonography, the cartilage thickness will be measured in 100 healthy individuals. Baseline cartilage values will be linked to the various domains of the KOOS score to evaluate early cartilage degeneration and its impact on function. This research will address the gap in Indian-specific data, including early detection and management of KOA and improving clinical decision-making for better outcomes and quality of life. • Establish normative knee cartilage thickness in healthy Indian population using USG. • Helps identify KOA in early stages through USG-based cartilage thickness evaluation • Enables clinicians to target rehabilitation efforts effectively and potentially improve patients' outcomes and quality of life.http://www.sciencedirect.com/science/article/pii/S2215016125000275Knee cartilage height evaluation using Ultrasound
spellingShingle Dias Tina Thomas
Charu Eapen
Atmananda S. Hegde
Prajwal Prabhudev Mane
Ajit R. Mahale
A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomes
MethodsX
Knee cartilage height evaluation using Ultrasound
title A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomes
title_full A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomes
title_fullStr A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomes
title_full_unstemmed A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomes
title_short A protocol to assess the Knee cartilage thickness in healthy older adults and analyze its correlation with patient-reported outcomes
title_sort protocol to assess the knee cartilage thickness in healthy older adults and analyze its correlation with patient reported outcomes
topic Knee cartilage height evaluation using Ultrasound
url http://www.sciencedirect.com/science/article/pii/S2215016125000275
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