Risk thresholds for soft versus hard cardiovascular disease outcome models for initiating statin therapy among Chinese adults: a cost-utility analysis

Risk thresholds for soft versus hard cardiovascular disease outcome models for initiating statin therapy among Chinese adults: a cost-utility analysis

Abstract Background Current guidelines for atherosclerotic cardiovascular disease (ASCVD) primary prevention mostly recommend risk scores that predict risk of non-fatal myocardial infarction, fatal ischemic heart disease (IHD), and fatal or non-fatal ischemic stroke (hard outcomes), ignoring the bur...

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Main Authors: Zhijia Sun, Haijun Zhang, Yinqi Ding, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Yiping Chen, Huaidong Du, Dan Huang, Xiaoming Yang, Maxim Barnard, Robert Clarke, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, on behalf of the China Kadoorie Biobank Collaborative Group
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medicine
Subjects:
Cardiovascular disease
Cost-utility analysis
Primary prevention
Hydroxymethylglutaryl-CoA reductase inhibitors
China
Online Access:https://doi.org/10.1186/s12916-025-04222-8
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