VOPP1::EGFR fusion is associated with NFκB pathway activation in a glioneural tumor with histological features of ganglioglioma

VOPP1::EGFR fusion is associated with NFκB pathway activation in a glioneural tumor with histological features of ganglioglioma

Abstract Glioneural tumors are primary brain tumors that consist of both neural and glial neoplastic cells, often presenting with seizures and primarily affecting children and young adults. Specifically, gangliogliomas are composed of neoplastic ganglion and glial cells, accompanied by other charact...

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Bibliographic Details
Main Authors: Max Braune, Mathias Stiller, Cordula Scherlach, Florian Wilhelmy, Katja Jähne, Wolf C. Müller, Alonso Barrantes-Freer
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Acta Neuropathologica Communications
Subjects:
VOPP1
EGFR
Ganglioglioma
Gene fusion
NFκB
Online Access:https://doi.org/10.1186/s40478-025-01994-1
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