Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy
We describe a patient with chronic inflammatory demyelinating polyneuropathy (CIDP) in which an adduction deficit and ptosis in the left eye presented several years before the polyneuropathy. A 52-year-old man presented with a 14-year history of unremitting diplopia, adduction deficit, and ptosis in...
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/769429 |
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| author | Rossella Spataro Vincenzo La Bella |
| author_facet | Rossella Spataro Vincenzo La Bella |
| author_sort | Rossella Spataro |
| collection | DOAJ |
| description | We describe a patient with chronic inflammatory demyelinating polyneuropathy (CIDP) in which an adduction deficit and ptosis in the left eye presented several years before the polyneuropathy. A 52-year-old man presented with a 14-year history of unremitting diplopia, adduction deficit, and ptosis in the left eye. At the age of 45 a mild bilateral foot drop and impaired sensation in the four limbs appeared, with these symptoms showing a progressive course. The diagnostic workup included EMG/ENG which demonstrated reduced conduction velocity with bilateral and symmetrical sensory and motor involvement. Cerebrospinal fluid studies revealed a cytoalbuminologic dissociation. A prolonged treatment with corticosteroids allowed a significant improvement of the limb weakness. Diplopia and ptosis remained unchanged. This unusual form of CIDP presented as a long-lasting isolated cranial nerve palsy. A diagnostic workup for CIDP should therefore be performed in those patients in which an isolated and unremitting cranial nerve palsy cannot be explained by common causes. |
| format | Article |
| id | doaj-art-22f90b83f3454063a83f9b0d10033c51 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
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| series | Case Reports in Medicine |
| spelling | doaj-art-22f90b83f3454063a83f9b0d10033c512025-02-03T01:09:46ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/769429769429Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating PolyneuropathyRossella Spataro0Vincenzo La Bella1ALS Clinical Research Center, Bio.Ne.C, University of Palermo, 90129 Palermo, ItalyALS Clinical Research Center, Bio.Ne.C, University of Palermo, 90129 Palermo, ItalyWe describe a patient with chronic inflammatory demyelinating polyneuropathy (CIDP) in which an adduction deficit and ptosis in the left eye presented several years before the polyneuropathy. A 52-year-old man presented with a 14-year history of unremitting diplopia, adduction deficit, and ptosis in the left eye. At the age of 45 a mild bilateral foot drop and impaired sensation in the four limbs appeared, with these symptoms showing a progressive course. The diagnostic workup included EMG/ENG which demonstrated reduced conduction velocity with bilateral and symmetrical sensory and motor involvement. Cerebrospinal fluid studies revealed a cytoalbuminologic dissociation. A prolonged treatment with corticosteroids allowed a significant improvement of the limb weakness. Diplopia and ptosis remained unchanged. This unusual form of CIDP presented as a long-lasting isolated cranial nerve palsy. A diagnostic workup for CIDP should therefore be performed in those patients in which an isolated and unremitting cranial nerve palsy cannot be explained by common causes.http://dx.doi.org/10.1155/2015/769429 |
| spellingShingle | Rossella Spataro Vincenzo La Bella Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy Case Reports in Medicine |
| title | Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy |
| title_full | Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy |
| title_fullStr | Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy |
| title_full_unstemmed | Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy |
| title_short | Long-Lasting Cranial Nerve III Palsy as a Presenting Feature of Chronic Inflammatory Demyelinating Polyneuropathy |
| title_sort | long lasting cranial nerve iii palsy as a presenting feature of chronic inflammatory demyelinating polyneuropathy |
| url | http://dx.doi.org/10.1155/2015/769429 |
| work_keys_str_mv | AT rossellaspataro longlastingcranialnerveiiipalsyasapresentingfeatureofchronicinflammatorydemyelinatingpolyneuropathy AT vincenzolabella longlastingcranialnerveiiipalsyasapresentingfeatureofchronicinflammatorydemyelinatingpolyneuropathy |