Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications

The effects of physical activity on brain function, the mechanisms involved, adaptations, and clinical implications are topics of great importance given the increasingly common sedentary lifestyle. This paper explores these relationships, starting with the evolutionary aspects of brain development...

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Main Authors: Dariusz Fabian, Klaudia Maria Kufel, Mateusz Teofilak, Natalia Maria Smyl, Olga Śpiołek, Jan Siwiec, Aleksandra Słowikowska, Julia Szatkowska, Marcelina Paula Sztyler-Krąkowska, Agnieszka Alicja Wąsowicz, Franciszek Kędziora
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2025-01-01
Series:Quality in Sport
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Online Access:https://apcz.umk.pl/QS/article/view/57569
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author Dariusz Fabian
Klaudia Maria Kufel
Mateusz Teofilak
Natalia Maria Smyl
Olga Śpiołek
Jan Siwiec
Aleksandra Słowikowska
Julia Szatkowska
Marcelina Paula Sztyler-Krąkowska
Agnieszka Alicja Wąsowicz
Franciszek Kędziora
author_facet Dariusz Fabian
Klaudia Maria Kufel
Mateusz Teofilak
Natalia Maria Smyl
Olga Śpiołek
Jan Siwiec
Aleksandra Słowikowska
Julia Szatkowska
Marcelina Paula Sztyler-Krąkowska
Agnieszka Alicja Wąsowicz
Franciszek Kędziora
author_sort Dariusz Fabian
collection DOAJ
description The effects of physical activity on brain function, the mechanisms involved, adaptations, and clinical implications are topics of great importance given the increasingly common sedentary lifestyle. This paper explores these relationships, starting with the evolutionary aspects of brain development in the context of physical activity. It discusses a variety of forms of exercise, from intense exercise to daily NEAT (non-exercise activity thermogenesis). A key issue is neuroplasticity, which plays an important role in adaptation to external stimuli. The article identifies key neurotrophic factors, such as BDNF (brain-derived neurotrophic factor) and VEGF (vascular endothelial growth factor), which are regulated by physical activity and contribute to improved cognitive function and mental health. The paper demonstrates the multifaceted effects of physical activity on neuroplasticity and brain health.
format Article
id doaj-art-22e1d0fd53f24517b50a10585d508db3
institution Kabale University
issn 2450-3118
language English
publishDate 2025-01-01
publisher Nicolaus Copernicus University in Toruń
record_format Article
series Quality in Sport
spelling doaj-art-22e1d0fd53f24517b50a10585d508db32025-01-23T08:24:41ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2025.37.57569Effects of physical activity on brain function: Mechanisms, adaptations and clinical implicationsDariusz Fabian0https://orcid.org/0009-0006-7241-7245Klaudia Maria Kufel1https://orcid.org/0009-0000-9873-6582Mateusz Teofilak2https://orcid.org/0009-0007-3902-2484Natalia Maria Smyl3https://orcid.org/0009-0003-9571-3432Olga Śpiołek4https://orcid.org/0009-0008-6271-1242Jan Siwiec5https://orcid.org/0000-0002-7193-7074Aleksandra Słowikowska6https://orcid.org/0009-0004-3705-822XJulia Szatkowska7https://orcid.org/0009-0007-5084-9378Marcelina Paula Sztyler-Krąkowska8https://orcid.org/0009-0004-4817-9537Agnieszka Alicja Wąsowicz9https://orcid.org/0009-0008-3256-793XFranciszek Kędziora10https://orcid.org/0009-0003-7833-1985Specialist Provincial Hospital in Ciechanów, Powstańców Wielkopolskich 2, 06-400 CiechanówStudent Scientific Society of Physiology, Department of Physiology, Institute of Medical Sciences, University of Opole, 45040 Opole, PolandMiędzyleski Specialist Hospital in Warsaw, Bursztynowa 2, 04-749 Warsaw, PolandJohn Paul II Western Hospital in Grodzisk Mazowiecki, Daleka 11, 05-825 Grodzisk Mazowiecki, PolandLUX MED Sp. z o.o., Szturmowa 2, 02-678 Warsaw, PolandMiędzyleski Specialist Hospital in Warsaw, Bursztynowa 2, 04-749 Warsaw, PolandNational Medical Institute of the Ministry of the Interior and Administration, Wołoska 137, 02- 507 Warsaw, PolandHospital of Our Lady of Perpetual Help in Wołomin, Gdyńska 1/3, 05-200 Wołomin, PolandDr Anna Gostynska Wolski Hospital, Independent Public Health Care Institution, Marcina Kasprzaka 17, 01-211 Warsaw, PolandNational Medical Institute of the Ministry of the Interior and Administration, Wołoska 137, 02- 507 Warsaw, PolandMedical University of Białystok, Jana Kilińskiego 1, 15-089 Białystok, Poland The effects of physical activity on brain function, the mechanisms involved, adaptations, and clinical implications are topics of great importance given the increasingly common sedentary lifestyle. This paper explores these relationships, starting with the evolutionary aspects of brain development in the context of physical activity. It discusses a variety of forms of exercise, from intense exercise to daily NEAT (non-exercise activity thermogenesis). A key issue is neuroplasticity, which plays an important role in adaptation to external stimuli. The article identifies key neurotrophic factors, such as BDNF (brain-derived neurotrophic factor) and VEGF (vascular endothelial growth factor), which are regulated by physical activity and contribute to improved cognitive function and mental health. The paper demonstrates the multifaceted effects of physical activity on neuroplasticity and brain health. https://apcz.umk.pl/QS/article/view/57569brainphysical activitybrain plasticityneuroplasticityBDNFVEGF
spellingShingle Dariusz Fabian
Klaudia Maria Kufel
Mateusz Teofilak
Natalia Maria Smyl
Olga Śpiołek
Jan Siwiec
Aleksandra Słowikowska
Julia Szatkowska
Marcelina Paula Sztyler-Krąkowska
Agnieszka Alicja Wąsowicz
Franciszek Kędziora
Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications
Quality in Sport
brain
physical activity
brain plasticity
neuroplasticity
BDNF
VEGF
title Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications
title_full Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications
title_fullStr Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications
title_full_unstemmed Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications
title_short Effects of physical activity on brain function: Mechanisms, adaptations and clinical implications
title_sort effects of physical activity on brain function mechanisms adaptations and clinical implications
topic brain
physical activity
brain plasticity
neuroplasticity
BDNF
VEGF
url https://apcz.umk.pl/QS/article/view/57569
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