Role of Educational Level in Kidney Transplant Outcomes

<b>Background</b>: Kidney transplantation outcomes are correlated to many factors, including the socioeconomics conditions and the educational level. <b>Methods</b>: We evaluated the role of educational level on patient and graft survival in a population of 456 kidney transpl...

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Main Authors: Francesco Leonforte, Pierfrancesco Veroux, Antonio Mistretta, Alessia Giaquinta, Martina Maria Giambra, Domenico Zerbo, Giuseppe Roscitano, Concetta De Pasquale, Maria Luisa Pistorio, Antonio D’Anna, Carmelo Cusmano, Roberta Granata, Giordana Riccioli, Marianna Scribano, Massimiliano Veroux
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/4/916
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Summary:<b>Background</b>: Kidney transplantation outcomes are correlated to many factors, including the socioeconomics conditions and the educational level. <b>Methods</b>: We evaluated the role of educational level on patient and graft survival in a population of 456 kidney transplant recipients. Patients were divided into two groups on the basis of their pre-transplant educational status: patients with primary education (elementary or middle school, as low education) were compared with patients with a secondary school education (high school or a university degree, as high education). <b>Results</b>: Among the 456 patients considered for this analysis, 161 patients had a low educational status, and 295 had a high educational status. Patients with a low educational status were more rarely employed (66.1% vs. 32.5%, <i>p</i> < 0.001), with a high rate of retired patients compared to high-educational status patients (35.6% vs. 10.6%, <i>p</i> < 0.001). Although the educational status did not influence the graft function, the 1-year (88.1% vs. 96.2%, <i>p</i> = 0.0008), 5-year (77.6% vs. 88.8%, <i>p</i> = 0.001), and 10-year (62.1% vs. 75%, <i>p</i> = 0.003) graft survival rates were significantly lower in patients with low educational status compared with high-educational status patients, respectively. Patient survival at 1-year (94.4% vs. 97.6%, <i>p</i> = 0.073), 5-year (85% vs. 92.5%, <i>p</i> = 0.011), and 10-year (75.7% vs. 83.4%, <i>p</i> = 0.042) follow-up was significantly lower in patients with low educational status. <b>Conclusions</b>: Low socioeconomic conditions and educational level had a negative impact on kidney transplant outcomes. Improving access to education and providing targeted educational support and health literacy could enhance treatment adherence and reduce disparities in transplant outcomes.
ISSN:2227-9059