Therapeutic potential of sulforaphane: modulation of NRF2-mediated PI3/AKT/mTOR pathway in oral fibrosis
Oral Submucous Fibrosis is a potentially malignant disorder caused by habitual areca nut chewing, which contributes to the dispersion of active alkaloids into subepithelial tissues, stimulating excessive extracellular matrix deposition. Various treatment modalities are available; however, their eff...
Saved in:
| Main Authors: | Pooja Narain Adtani, Rajasekaran Subbarayan, Rupendra Shrestha, Walid Elsayed |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universidade Estadual Paulista
2024-04-01
|
| Series: | Brazilian Dental Science |
| Online Access: | https://ojs.ict.unesp.br/index.php/cob/article/view/4172 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Sulforaphane from Brassica Oleracea Induces Apoptosis in Oral Squamous Carcinoma Cells via p53 Activation and Mitochondrial Membrane Potential Dysfunction
by: Pooja Narain Adtani, et al.
Published: (2025-03-01) -
The Emerging Role and Clinical Significance of PI3K-Akt-mTOR in Rhabdomyosarcoma
by: Ilaria Versari, et al.
Published: (2025-02-01) -
PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment
by: Mingyang Jiang, et al.
Published: (2025-08-01) -
AURKB and PI3K/AKT/mTOR pathways converge to regulate TERT expression
by: Grace Lim, et al.
Published: (2025-08-01) -
Research on the role and mechanism of the PI3K/Akt/mTOR signalling pathway in osteoporosis
by: Chuanlong Liu, et al.
Published: (2025-05-01)