Eosinophilic esophagitis in the “atopic march”: dupilumab as an “umbrella” strategy for multiple coexisting atopic diseases

Eosinophilic esophagitis in the “atopic march”: dupilumab as an “umbrella” strategy for multiple coexisting atopic diseases

Dupilumab is a monoclonal antibody targeting interleukin-4 and interleukin-13, approved for the treatment of multiple T2 diseases and more recently for Eosinophilic Esophagitis (EoE). EoE is a chronic T2 inflammatory disease, believed to be a member of the “atopic march”, due to multiple similaritie...

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Bibliographic Details
Main Authors: Nicola Lutzu, Agnese Favale, Mauro Demurtas, Stefano Del Giacco, Sara Onali, Massimo Claudio Fantini
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
Subjects:
esophagitis
atopic march
anti-IL4
anti-IL13
eosinophils
dupilumab
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1513417/full
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