Synthesis of bioactive quinazolin-4(3H)-one derivatives via microwave activation tailored by phase-transfer catalysis

Synthesis of bioactive quinazolin-4(3H)-one derivatives via microwave activation tailored by phase-transfer catalysis

A series of nine new 2,3-disubstituted 4(3H)-quinazolin-4-one derivatives was furnished starting from the 2-propyl-4(3H)-quinazo-line-4-one (2). The reinvestigation of the key starting quinazolinone 2 was performed under microwave irradiation (MW) and solvent-free conditions. Combination of MW and p...

Full description

Saved in:
Bibliographic Details
Main Authors: El-Badry Yaser A., El-Hashash Mahr A., Al-Ali Khalil
Format: Article
Language:English
Published: Sciendo 2020-06-01
Series:Acta Pharmaceutica
Subjects:
solid-liquid transfer catalysis
microwave-assisted reaction
2-propylquinazolinone
n-alkylation
2, 3-disubstituted quinazolinones
anticancer activity
Online Access:https://doi.org/10.2478/acph-2020-0001
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.2478/acph-2020-0001

Similar Items