Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis

Bacterial peritonitis is a common complication of peritoneal dialysis, but fungal peritonitis is unusual and is mostly due to Candida species. Peritonitis due to Histoplasma capsulatum is rare and we report one such case. A 63-year-old female presented with progressively worsening abdominal pain, fe...

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Main Authors: Asjad Sardar, Bijin Thajudeen, Pradeep V. Kadambi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2018/8015230
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author Asjad Sardar
Bijin Thajudeen
Pradeep V. Kadambi
author_facet Asjad Sardar
Bijin Thajudeen
Pradeep V. Kadambi
author_sort Asjad Sardar
collection DOAJ
description Bacterial peritonitis is a common complication of peritoneal dialysis, but fungal peritonitis is unusual and is mostly due to Candida species. Peritonitis due to Histoplasma capsulatum is rare and we report one such case. A 63-year-old female presented with progressively worsening abdominal pain, fever, and altered mental status. She had end-stage renal disease and had been on peritoneal dialysis for 4 years. She had abdominal tenderness without rebound or guarding. Laboratory studies and CT of abdomen were significant for leukocytosis and peritoneal membrane thickening, respectively. Peritoneal dialysis fluid study was consistent with peritonitis and culture of the fluid grew Histoplasma capsulatum. Treatment recommendations include removal of catheter and initiation of antifungal therapy. With the availability of newer antifungals, medical management without removal of PD catheter is possible, but at the same time if there is no response to treatment within a week, PD catheter should be removed promptly.
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institution Kabale University
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publishDate 2018-01-01
publisher Wiley
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series Case Reports in Nephrology
spelling doaj-art-224d36d054a9438592e296779f857e9b2025-02-03T06:01:09ZengWileyCase Reports in Nephrology2090-66412090-665X2018-01-01201810.1155/2018/80152308015230Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal DialysisAsjad Sardar0Bijin Thajudeen1Pradeep V. Kadambi2Division of Nephrology, Department of Medicine, University of Arizona, Tucson, AZ, USADivision of Nephrology, Department of Medicine, University of Arizona, Tucson, AZ, USADepartment of Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL, USABacterial peritonitis is a common complication of peritoneal dialysis, but fungal peritonitis is unusual and is mostly due to Candida species. Peritonitis due to Histoplasma capsulatum is rare and we report one such case. A 63-year-old female presented with progressively worsening abdominal pain, fever, and altered mental status. She had end-stage renal disease and had been on peritoneal dialysis for 4 years. She had abdominal tenderness without rebound or guarding. Laboratory studies and CT of abdomen were significant for leukocytosis and peritoneal membrane thickening, respectively. Peritoneal dialysis fluid study was consistent with peritonitis and culture of the fluid grew Histoplasma capsulatum. Treatment recommendations include removal of catheter and initiation of antifungal therapy. With the availability of newer antifungals, medical management without removal of PD catheter is possible, but at the same time if there is no response to treatment within a week, PD catheter should be removed promptly.http://dx.doi.org/10.1155/2018/8015230
spellingShingle Asjad Sardar
Bijin Thajudeen
Pradeep V. Kadambi
Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis
Case Reports in Nephrology
title Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis
title_full Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis
title_fullStr Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis
title_full_unstemmed Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis
title_short Histoplasma Peritonitis: An Extremely Rare Complication of Peritoneal Dialysis
title_sort histoplasma peritonitis an extremely rare complication of peritoneal dialysis
url http://dx.doi.org/10.1155/2018/8015230
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AT bijinthajudeen histoplasmaperitonitisanextremelyrarecomplicationofperitonealdialysis
AT pradeepvkadambi histoplasmaperitonitisanextremelyrarecomplicationofperitonealdialysis