Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report
Primary Sjögren syndrome (SS) is a chronic inflammatory systemic autoimmune disease with a high risk of malignancy development, namely, lymphoproliferative neoplasms. Few studies also reported a high risk of solid cancers; however, the coexistence of primary SS and pancreatic cancer has been rarely...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2021/9915881 |
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| _version_ | 1832560584705441792 |
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| author | Daniela Oliveira Vanessa Chaves José Carlos Martins Carlos Vaz Miguel Bernardes Jorge Almeida |
| author_facet | Daniela Oliveira Vanessa Chaves José Carlos Martins Carlos Vaz Miguel Bernardes Jorge Almeida |
| author_sort | Daniela Oliveira |
| collection | DOAJ |
| description | Primary Sjögren syndrome (SS) is a chronic inflammatory systemic autoimmune disease with a high risk of malignancy development, namely, lymphoproliferative neoplasms. Few studies also reported a high risk of solid cancers; however, the coexistence of primary SS and pancreatic cancer has been rarely described. In this paper, we aim to describe a case of a 59-year-old woman who was an active smoker with sicca symptoms and symmetrical polyarthritis and was diagnosed with primary SS two years before the development of metastatic pancreatic adenocarcinoma. Despite institution of chemotherapy, the patient succumbed to the malignancy. Besides that, we explore the link between primary SS and solid cancers including the main predictors of malignancy and the role of primary SS as a paraneoplastic syndrome. Patients with primary SS should be closely monitored for malignancy, not only for hematological cancer, but also for solid tumors. Further research is necessary to understand which are the predictors of cancer proliferation in primary SS patients. |
| format | Article |
| id | doaj-art-2229df07f3064c7c9ec41e8fc2cf0efc |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-2229df07f3064c7c9ec41e8fc2cf0efc2025-02-03T01:27:06ZengWileyCase Reports in Rheumatology2090-68892090-68972021-01-01202110.1155/2021/99158819915881Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case ReportDaniela Oliveira0Vanessa Chaves1José Carlos Martins2Carlos Vaz3Miguel Bernardes4Jorge Almeida5Rheumatology Department, University Hospital Center of São João, Porto, PortugalInternal Medicine Department, University Hospital Center of São João, Porto, PortugalInternal Medicine Department, University Hospital Center of São João, Porto, PortugalRheumatology Department, University Hospital Center of São João, Porto, PortugalRheumatology Department, University Hospital Center of São João, Porto, PortugalInternal Medicine Department, University Hospital Center of São João, Porto, PortugalPrimary Sjögren syndrome (SS) is a chronic inflammatory systemic autoimmune disease with a high risk of malignancy development, namely, lymphoproliferative neoplasms. Few studies also reported a high risk of solid cancers; however, the coexistence of primary SS and pancreatic cancer has been rarely described. In this paper, we aim to describe a case of a 59-year-old woman who was an active smoker with sicca symptoms and symmetrical polyarthritis and was diagnosed with primary SS two years before the development of metastatic pancreatic adenocarcinoma. Despite institution of chemotherapy, the patient succumbed to the malignancy. Besides that, we explore the link between primary SS and solid cancers including the main predictors of malignancy and the role of primary SS as a paraneoplastic syndrome. Patients with primary SS should be closely monitored for malignancy, not only for hematological cancer, but also for solid tumors. Further research is necessary to understand which are the predictors of cancer proliferation in primary SS patients.http://dx.doi.org/10.1155/2021/9915881 |
| spellingShingle | Daniela Oliveira Vanessa Chaves José Carlos Martins Carlos Vaz Miguel Bernardes Jorge Almeida Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report Case Reports in Rheumatology |
| title | Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report |
| title_full | Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report |
| title_fullStr | Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report |
| title_full_unstemmed | Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report |
| title_short | Pancreatic Cancer and Primary Sjögren’s Syndrome: A Case Report |
| title_sort | pancreatic cancer and primary sjogren s syndrome a case report |
| url | http://dx.doi.org/10.1155/2021/9915881 |
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