Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review

Background. Patients infected with coronavirus disease 2019 (COVID-19) present with various clinical presentations with majority of them developing pulmonary complications. This study focuses on cardiac implications of COVID-19 which are less discussed and thus will help to address cardiac implicati...

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Main Authors: Rajaram Khanal, Shreeyash Raj Bhattarai, Kriti Basnet, Sangam Shah, Roman Dhital, Sanjit Kumar Sah, Sujan Poudel, Odalys Frontela, George Michel, Sima Marzban, Alfonso J. Rodriguez-Morales
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Interdisciplinary Perspectives on Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2022/9119930
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author Rajaram Khanal
Shreeyash Raj Bhattarai
Kriti Basnet
Sangam Shah
Roman Dhital
Sanjit Kumar Sah
Sujan Poudel
Odalys Frontela
George Michel
Sima Marzban
Alfonso J. Rodriguez-Morales
author_facet Rajaram Khanal
Shreeyash Raj Bhattarai
Kriti Basnet
Sangam Shah
Roman Dhital
Sanjit Kumar Sah
Sujan Poudel
Odalys Frontela
George Michel
Sima Marzban
Alfonso J. Rodriguez-Morales
author_sort Rajaram Khanal
collection DOAJ
description Background. Patients infected with coronavirus disease 2019 (COVID-19) present with various clinical presentations with majority of them developing pulmonary complications. This study focuses on cardiac implications of COVID-19 which are less discussed and thus will help to address cardiac implications of COVID-19. Methods. PubMed, PubMed Central, and Google Scholar were screened for articles which mentioned cardiac implications of COVID-19. NHLBI Study Quality Assessment Tools for the observational cohort and cross-sectional studies was used for assessing the risk of bias of our studies. Results. All 14 studies selected were good and had score of ≥9 by NHLBI Study Quality Assessment Tools. Cardiac complications of COVID-19 are common. They are associated with significant mortality. Also, people infected with COVID-19 with premorbid conditions such as cardiovascular diseases and diabetes mellitus have poor prognosis as compared to those without premorbid conditions. Cardiac biomarkers such as highly sensitive troponin I, creatinine, and creatinine kinase-MB on admission are good prognostic markers. Conclusions. Cardiac complications such as heart failure, myocardial injury, and arrhythmias are common among patients infected with COVID-19. Elevated cardiac markers and patients with cardiac complications require utmost care and continuous cardiac monitoring.
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spelling doaj-art-221ec1b13ba2449db98c3c1f17fc50692025-02-03T01:22:26ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-70982022-01-01202210.1155/2022/9119930Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic ReviewRajaram Khanal0Shreeyash Raj Bhattarai1Kriti Basnet2Sangam Shah3Roman Dhital4Sanjit Kumar Sah5Sujan Poudel6Odalys Frontela7George Michel8Sima Marzban9Alfonso J. Rodriguez-Morales10Department of CardiologyDivision of Research and Academic AffairsDivision of Research and Academic AffairsMaharajgunj Medical CampusDivision of Research and Academic AffairsDivision of Research and Academic AffairsDivision of Research and Academic AffairsProgram DirectorProgram DirectorDivision of Research and Academic AffairsGrupo de Investigación BiomedicinaBackground. Patients infected with coronavirus disease 2019 (COVID-19) present with various clinical presentations with majority of them developing pulmonary complications. This study focuses on cardiac implications of COVID-19 which are less discussed and thus will help to address cardiac implications of COVID-19. Methods. PubMed, PubMed Central, and Google Scholar were screened for articles which mentioned cardiac implications of COVID-19. NHLBI Study Quality Assessment Tools for the observational cohort and cross-sectional studies was used for assessing the risk of bias of our studies. Results. All 14 studies selected were good and had score of ≥9 by NHLBI Study Quality Assessment Tools. Cardiac complications of COVID-19 are common. They are associated with significant mortality. Also, people infected with COVID-19 with premorbid conditions such as cardiovascular diseases and diabetes mellitus have poor prognosis as compared to those without premorbid conditions. Cardiac biomarkers such as highly sensitive troponin I, creatinine, and creatinine kinase-MB on admission are good prognostic markers. Conclusions. Cardiac complications such as heart failure, myocardial injury, and arrhythmias are common among patients infected with COVID-19. Elevated cardiac markers and patients with cardiac complications require utmost care and continuous cardiac monitoring.http://dx.doi.org/10.1155/2022/9119930
spellingShingle Rajaram Khanal
Shreeyash Raj Bhattarai
Kriti Basnet
Sangam Shah
Roman Dhital
Sanjit Kumar Sah
Sujan Poudel
Odalys Frontela
George Michel
Sima Marzban
Alfonso J. Rodriguez-Morales
Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review
Interdisciplinary Perspectives on Infectious Diseases
title Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review
title_full Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review
title_fullStr Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review
title_full_unstemmed Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review
title_short Cardiac Implications of COVID-19 in Deceased and Recovered Patients: A Systematic Review
title_sort cardiac implications of covid 19 in deceased and recovered patients a systematic review
url http://dx.doi.org/10.1155/2022/9119930
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